Chargers vs Cardinals Odds, Lines, Spreads & Totals 2026

Cardinals
Chargers
Sunday September 13, 2026 at 4:25 PM ET
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Cardinals Lineup
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Chargers Lineup
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Cardinals News
#2 WR
Marvin Harrison: Held to one catch in win
Sep 13th
Harrison brought in one of three targets for 33 yards in the Cardinals' 26-14 win over the Chargers on Sunday.
#1 WR
Michael Wilson: Opens season with five catches
Sep 13th
Wilson secured five of seven targets for 56 yards in the Cardinals' 26-14 win over the Chargers on Sunday.
#2 RB
Tyler Allgeier: Robust workload in Week 1 win
Sep 13th
Allgeier rushed 17 times for 61 yards and brought in both targets for nine yards in the Cardinals' 26-14 win over the Chargers on Sunday.
#1 QB
Jacoby Brissett: Stellar numbers in Week 1 upset
Sep 13th
Brissett completed 27 of 37 passes for 277 yards with a touchdown and no interceptions while rushing six times for 14 yards in the Cardinals' 26-14 win over the Chargers on Sunday.
#1 TE
Trey McBride: Signature effort in Week 1 upset
Sep 13th
McBride brought in nine of 12 targets for 95 yards and a touchdown in the Cardinals' 26-14 win over the Chargers on Sunday.
#1 RB
Jeremiyah Love: Scores TD in NFL debut
Sep 13th
Love rushed 11 times for 41 yards and a touchdown while bringing in two of four targets for nine yards in the Cardinals' 26-14 win over the Chargers on Sunday.
#3 FS
Kitan Crawford: Exits with ankle injury
Sep 13th
Crawford (ankle) is questionable to return to Sunday's game against the Chargers, Josh Weinfuss of ESPN.com reports.
#3 QB
Carson Beck: Emergency QB to start season
Sep 13th
Beck (coach's decision) is inactive as the emergency third quarterback for Sunday's game against the Chargers.
#1 RG
Isaiah Adams: Ruled out due to knee injury
Sep 11th
Adams (knee) has been ruled out for Sunday's game against the Cardinals.
#1 LCB
Garrett Williams: Won't suit up against Chargers
Sep 11th
Williams (Achilles) is listed as out for Sunday's game against the Chargers.
#2 SS
Dadrion Taylor-Demerson: Won't play against Chargers
Sep 11th
Taylor-Demerson (ribs) is listed as out for Sunday's game against the Chargers.
#1 P
Blake Gillikin: Practices in full Wednesday
Sep 9th
Gillikin (groin) was a full participant in Wednesday's practice, Bo Brack of GoPHNX.com reports.
#3 LCB
Will Johnson: Logs full practice Wednesday
Sep 9th
Johnson (lower body) was a full participant in Wednesday's practice, Bo Brack of GoPHNX.com reports.
#3 LDT
Zach Carter: Lands on IR with designation to return
Aug 31st
The Cardinals placed Carter (knee) on injured reserve Sunday with a designation to return, Darren Urban of the team's official site reports.
#4 TE
Tip Reiman: Moved to reserve/PUP
Aug 30th
The Cardinals moved Reiman (ankle) from the active/PUP list to the reserve/PUP list Sunday, Darren Urban of the team's official site reports.
#4 RB
James Conner: Moves to IR, designation to return
Aug 30th
The Cardinals are placing Conner (foot) on injured reserve with a designation to return, John Gambadoro of Arizona Sports 98.7 FM Phoenix reports.
#3 TE
Hunter Long: Traded to Arizona
Aug 30th
Long has been traded from Jacksonville to the Cardinals, Ian Rapoport of NFL Network reports.
LAC
Chargers News
#2 RB
Keaton Mitchell: Unimpressive in Chargers debut
Sep 13th
Mitchell rushed four times for nine yards in a Week 1 loss to Arizona on Sunday. He added 47 yards on two kickoff returns.
#1 QB
Justin Herbert: Disappointing in Week 1 loss
Sep 13th
Herbert completed 17 of 27 passes for 209 yards with one touchdown and one interception while adding five rushes for 29 yards in the Chargers' 26-14 loss to the Cardinals on Sunday.
#1 RB
Omarion Hampton: Quiet after first-half TD
Sep 13th
Hampton rushed 12 times for 43 yards and a touchdown and lost a fumble in the Chargers' 26-14 loss to the Cardinals on Sunday.
#2 WR
Quentin Johnston: Catches two passes in loss
Sep 13th
Johnston caught two of his six targets for 17 yards in Sunday's 26-14 loss to the Cardinals.
#1 WR
Ladd McConkey: No update on chest injury after loss
Sep 13th
Head coach Jim Harbaugh didn't have a postgame update on McConkey (chest), who exited in the second half of Sunday's 26-14 loss to the Cardinals, Kris Rhim of ESPN.com reports.
#7 WR
KeAndre Lambert-Smith: Questionable to return, hamstring issue
Sep 13th
Lambert-Smith (hamstring) is questionable to return to Sunday's game against the Cardinals.
#1 FS
Elijah Molden: Suffers hamstring injury
Sep 13th
Molden (hamstring) is questionable to return to Sunday's game against the Cardinals.
#1 LOLB
Tuli Tuipulotu: Green light to play Week 1
Sep 13th
Tuipulotu (hip) is active for Sunday's game against the Cardinals, Eric Smith of the Chargers' official site reports.
#2 RCB
Deane Leonard: Not playing Week 1
Sep 11th
Leonard has been ruled out ahead of Sunday's game against the Cardinals due to an abdominal injury.
#4 WR
Brenen Thompson: Good to go for Week 1
Sep 11th
Thompson (hip) doesn't carry an injury designation into Sunday's game against the Cardinals.
#1 LT
Rashawn Slater: Not listed on injury report
Sep 9th
Slater (undisclosed) wasn't listed on the Chargers' injury report Wednesday.
#1 K
Cameron Dicker: Fades Wednesday's injury report
Sep 9th
Dicker (undisclosed) was not listed on Wednesday's injury report.
#3 WR
Tre' Harris: Fully healthy for Week 1
Sep 9th
Harris (undisclosed) is not listed on the Week 1 injury report Wednesday.
#3 RILB
Denzel Perryman: Sent to IR
Sep 1st
The Chargers placed Perryman (undisclosed) on injured reserve Tuesday.
#4 LT
Isaiah World: Moved to reserve/non-football injury list
Aug 31st
The Chargers placed World (knee) on the reserve/non-football injury list Sunday.
#2 FB
Scott Matlock: Placed on IR, designated to return
Aug 31st
Matlock (undisclosed) was placed on injured reserve by the Chargers on Sunday with a designation to return.
#2 SS
Tony Jefferson: Sticking around Los Angeles
Aug 30th
Jefferson will be a member of the Chargers' initial 53-man roster, Adam Schefter of ESPN reports.
#3 LT
Branson Taylor: Placed on IR, designated to return
Aug 30th
The Chargers placed Taylor (undisclosed) on injured reserve Sunday with a designation to return, Ian Rapoport of ESPN and NFL Network reports.
#2 QB
Trey Lance: Set to serve as No. 2 QB
Aug 30th
Lance has won the Chargers' backup quarterback job, Matt Zenitz of CBSSports.com reports.