Los Angeles Chargers at Buffalo Bills 
Betting Odds, Picks, and Predictions for Week 3
With OUR Chicago Bears taking their talents to Monday Night, I've had my focus directed to this beauty of a game. We have a West Coast team traveling east in an early window, and one of those teams looking like a complete mess (L.A.), while the other (Buffalo) has looked nearly unstoppable. Everything on the surface points to a big Bills win, but will it play out that way? Let's dig in.
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Chargers vs Bills Betting Odds
- Spread: Bills -7 (BetRivers), Chargers +7.5 (FanDuel)
- Moneyline: Bills -335 (Caesars), Chargers +295 (FanDuel)
- Total: Over 50 (BetMGM), Under 50.5 (Bet365)
Oh, hey, stop me if you've heard this before: weather will be a factor in Buffalo. However, we aren't talking about inches of snow this time, we are talking about wind and rain with a strong Nor'easter rolling in. If the game in Chicago last week was any indication, this total is way too high, and that will be a consideration for my top pick in this game. I also think the weather could be a big equalizer for the Chargers.....perhaps Mother Nature is the only way to stop Josh Allen?
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Chargers vs Bills Week 3 Picks
When was the last time a Jim Harbaugh team was winless at any point in the season, much less 0-2 with two horrid losses? The Chargers cannot be this bad, and I truly think going on the road will be a boost. Their "home" field in L.A. is hardly an advantage, and they will come into this game beyond desperate.
Josh Allen is the best player in football, and his Bills are rolling, but with weather potentially slowing things down and the Chargers coming in angry, I like the road team getting all these points. As mentioned above, I also lean to the under.
