Hotspots on this week's NFL injury report include Philadelphia's pass catchers, Gang Green's pass catchers, New England's defense, Carolina's cornerbacks and the Chargers' secondary.
Three starting running backs suffered significant injuries last week, but nearly all of the key 'questionables' for fantasy in Week 4 are wide receivers, including Terry McLaurin, Jalen Coker, Keenan Allen and Mike Evans. We'll discuss them all below, in addition to many others.
Make sure to keep up with NFL breaking news throughout the weekend, especially Sunday morning when inactive lists are released at 11:30 a.m. ET for the early games.
Below you'll find four different categories, with our lists including key offensive linemen and defensive players whose absences might impact fantasy decisions. The bottom section, for potential game-day decisions, is sorted by kickoff times. It can be used as a checklist/cheatsheet for Sunday when inactives come out and we need to adjust lineups.
Good to Go 💯
Players that missed their team's previous game are listed in bold.
Cleared to Play this Week
QB Lamar Jackson (back)
RB D'Andre Swift (knee)
RB Bucky Irving (glute)
RB Tony Pollard (ankle)
RB Jaylen Wright (foot/neck)
RB George Holani (rib)
RB Keaton Mitchell (ankle)
WR DJ Moore (shoulder)
WR Puka Nacua (abdomen)
WR Chris Godwin (ankle)
WR Keon Coleman (ankle)
WR Chris Bell (knee)
TE Chig Okonkwo (hamstring)
Puka Nacua will play Sunday against the Eagles. Sean McVay said Nacua "looked sharp" yesterday at practice, but the Rams are still working through how they
Hotspots on this week's NFL injury report include Philadelphia's pass catchers, Gang Green's pass catchers, New England's defense, Carolina's cornerbacks and the Chargers' secondary.
Three starting running backs suffered significant injuries last week, but nearly all of the key 'questionables' for fantasy in Week 4 are wide receivers, including Terry McLaurin, Jalen Coker, Keenan Allen and Mike Evans. We'll discuss them all below, in addition to many others.
Make sure to keep up with NFL breaking news throughout the weekend, especially Sunday morning when inactive lists are released at 11:30 a.m. ET for the early games.
Below you'll find four different categories, with our lists including key offensive linemen and defensive players whose absences might impact fantasy decisions. The bottom section, for potential game-day decisions, is sorted by kickoff times. It can be used as a checklist/cheatsheet for Sunday when inactives come out and we need to adjust lineups.
Good to Go 💯
Players that missed their team's previous game are listed in bold.
Cleared to Play this Week
QB Lamar Jackson (back)
RB D'Andre Swift (knee)
RB Bucky Irving (glute)
RB Tony Pollard (ankle)
RB Jaylen Wright (foot/neck)
RB George Holani (rib)
RB Keaton Mitchell (ankle)
WR DJ Moore (shoulder)
WR Puka Nacua (abdomen)
WR Chris Godwin (ankle)
WR Keon Coleman (ankle)
WR Chris Bell (knee)
TE Chig Okonkwo (hamstring)
Puka Nacua will play Sunday against the Eagles. Sean McVay said Nacua "looked sharp" yesterday at practice, but the Rams are still working through how they will navigate his snap count.
— Sarah Barshop (@sarahbarshop) October 2, 2026
Ruled Out/Doubtful 🚑
New absences listed in bold (guys that played in the previous game).
Out/Doubtful/IR
QB Jayden Daniels (elbow)
QB Caleb Williams (hamstring)
QB Baker Mayfield (thumb)
RB De'Von Achane (IR - ACL)
RB Breece Hall (quad/thigh)
RB Travis Etienne (IR - hamstring)
RB Rachaad White (shoulder)
RB Jadarian Price (chest)
WRs DeVonta Smith (ankle) & Hollywood Brown (ankle)
WR Justin Jefferson (ankle)
WR Adonai Mitchell (finger)
WR Caleb Douglas (ankle)
WR Xavier Legette (knee)
WR Colbie Young (knee)
WR Brenen Thompson (quad)
TE Dallas Goedert (knee)
TE Mason Taylor (thumb)
TE Terrance Ferguson (IR - ankle)
TEs Charlie Kolar (arm) & David Njoku (IR - knee)
TE Josh Oliver (IR - biceps)
Potential Workload Beneficiaries (From Injuries Above)
QB Marcus Mariota
QB Tyson Bagent / Case Keenum
QB Jalon Daniels
RBs Ollie Gordon & Jaylen Wright
RBs Braelon Allen & Isaiah Davis
RBs Alvin Kamara & Kendre Miller
RBs Jacory Croskey-Merritt & Austin Ekeler
RBs Emanuel Wilson & George Holani
WRs Dontayvion Wicks, Makai Lemon & Darius Cooper
WRs Jordan Addison, Jauan Jennings & Tai Felton
WRs Isaiah Williams, Sterling Shepard & Malik McClain
WRs Chris Bell, Kevin Coleman & Ryan Miller
WRs Brycen Tremayne & John Metchie
WR Dohnte Meyers & TE Mike Gesicki
TEs Zach Ertz & Johnny Mundt
TEs Kenyon Sadiq (back) & Jeremy Ruckert
TEs Tyler Higbee & Colby Parkinson (shoulder)
TEs Oronde Gadsden & Hayden Rucci
Key Defensive Players + Offensive Linemen
CB Christian Gonzalez (shoulder), DT Christian Barmore (shoulder)
LT Braxton Jones (knee)
DB Cam Lewis (D - leg)
C Ethan Pocic (knee), C Jovaughn Gwyn (leg), DE Trey Hendrickson (finger)
CB Jalen Davis (IR - hamstring), S Kyle Dugger (quad)
LB DeMarvion Overshown (hamstring), CB Cobie Durant (hamstring)
LB Azeez Al-Shaair (groin)
LT Josh Simmons (back)
DT Aaron Donald (back), CB Jaylen Watson (shoulder)
G Kayode Awosika (leg), DT Dalvin Tomlinson (hamstring)
G Jackson Powers-Johnson (groin)
LB Zack Baun (concussion)
DE Nick Bosa (calf)
G Sam Cosmi (concussion), S Nick Cross (illness)
CB Jaycee Horn (IR - quad), CB Mike Jackson (IR - groin)
Listed as Questionable - Should Play 👍
RB Tyjae Spears (ankle - FP on Friday / played last week)
WRs Zay Flowers (hamstring) & Chris Moore (ankle)
Truly Questionable / Game-Time Decisions 🤔
Players with key fantasy repercussions listed in bold.
London Game - 9:30 a.m. ET
WR Terry McLaurin (hamstring)
WR Keenan Allen (quad)
Commanders WR Terry McLaurin was an end-of-week addition to the injury report due to a hamstring injury suffered in practice. That doesn't sound promising, and it could push more targets toward Stefon Diggs, who has a promising slot matchup with struggling Colts cornerback Justin Walley.
The Commanders would also give Antonio Williams more playing time in McLaurin's absence, though perhaps not to the extent fantasy enthusiasts are hoping for. The Commanders have also been using Treylon Burks and Dyami Brown, rather than unleashing Williams in a larger role after his strong start to the season.
On the other side of the game, Colts WR Keenan Allen opened the week listed as a limited practice participant due to rest, but the Colts then listed him with a groin injury Thursday (LP) and Friday (DNP). It's hard to say if he tweaked something or the Colts are just being cautious... maybe some of both. Whatever the case, fantasy managers should be ready for a game-time call in case it comes to that. With Allen out, Josh Downs and Tyler Warren would have even stronger target-share projections than they already do. WR Laquon Treadwell was also a full-time player last week, but he saw just three targets and the Colts now have Ashton Dulin and Darius Slayton as options too.
Early Games
TE Kenyon Sadiq (back)
TE Eli Raridon (thigh)
It looks like all of the important fantasy news this weekend will pertain to the London game or the games with later kickoffs. Sadiq is listed as questionable, but he continued playing last week after taking a hard hit, and he then managed limited practices all of this week. He'll likely play.
Late-Afternoon Games
WR Mike Evans (rib)
WR Ladd McConkey (foot)
TE Colby Parkinson (shoulder/knee)
Both McConkey and Evans could come down to true game-time decisions. If I had to guess, both will play, with Evans a bit more likely to sit.
McConkey didn't run any routes or catch any passes with the rest of Chargers WRs during the period open to media. He stood and watched, but back at practice after missing yesterdays https://t.co/p75qEHSuzg pic.twitter.com/Qmz22mM3ZK
— Kris Rhim (@krisrhim1) October 2, 2026
#49ers WR Mike Evans (ribs) said he will give his best to try to play Sunday against the Broncos. He's listed as questionable but sounds like he has a plan to try to play with a sort of built in compression shirt with padding in it. Evans said he's played through a similar injury…
— Nick Wagoner (@nwagoner) October 2, 2026
Shoutout to ESPN's Nick Wagoner for asking the right questions and doing good reporting here.
Primetime Games
WR Jalen Coker (quad) - SNF
TE Noah Fant (abdomen) - MNF
Coker seems truly questionable, putting his fantasy managers in a tough spot where they'd only be able to choose players from SNF or MNF if Coker were to be ruled out in a game-time decision. Hopefully it won't come to that and we'll have a decent idea by Sunday morning.
Key Defensive Players + O-Linemen
OLB Josh Sweat (groin)
LT Ronnie Stanley (toe)
CB Christian Benford (toe)
RT Monroe Freeling (head), DT Lee Hunter (foot), DT Cam Jackson (knee)
LB Edgerrin Cooper (concussion)
S Ty Okada (hamstring)
LB Dre Greenlaw (quad)
S Derwin James (hamstring), CB Donte Jackson (head), S Elijah Molden (hamstring)
CB D.J. Reed (ribs)
LB Pete Werner (neck), DE Carl Granderson (ankle), LB Kaden Elliss (calf)
Banged-up secondary for the Chargers. Maybe this'll be the week JSN finally gets something going. https://t.co/XYvpIrrFvJ
— Jerry Donabedian (@Lurn2Reed) October 2, 2026
