Knowshon Moreno suddenly looks like the running back to own in Denver, even if it is by default.
Matt Forte is the No. 1 back in Chicago, but Michael Bush's emergence could relegate Forte to the sideline when the team is at the goal line.
Neither quarterback has looked great this preseason, but John Skelton might have the early edge on Kevin Kolb to be Arizona's starter.
Jahvid Best and Mikel Leshoure are battling to start at running back in Detroit, but the job might come down to who can stay healthy.
Maurice Jones-Drew tops our RB rankings for Week 17.
Ryan Mathews is even getting goal line carries now.
Johnny Knox is the latest Bears skill-position player to fall to injury this year,
Who will step up now that Greg Jennings won't be there to put that team on his back?
Matthew Stafford and the Lions get their shot at the injury-riddled Vikings secondary this week.
Matt Forte could be relegated to watching from the sidelines for the next month as he suffered a knee injury Sunday.
The Bucs expect to use Blount Force to try to beat the Panthers this week.
After a big game Sunday, Roy Helu looks to have taken over the starting job for the Redskins, though that's never a lock in Washington.
Thanksgiving Day Feast of Games
Do you start Tim Tebow on short rest this week given all the quarterback carnage?
Mike Shanahan's confounding use of his running backs might make him the Tony La Russa of the NFL - and not in a good way.
Cam Newton is back after the bye week.