This article is part of our Matchup Edge series.
Baltimore vs. Indianapolis
Open: 41 O/U, BAL -12.5
Press time: 41 O/U, BAL -13
Baltimore should absolutely flatten the Colts. Alex Collins has to carry one of the top projections of the week, particularly given his recent promotion in the passing game – an arrangement that should endure with Jeremy Maclin out this week. Joe Flacco should have a high floor against the Colts defense, and Mike Wallace would be the top suspect for catching his big gains. You do worry about the ceiling given that the Colts don't look capable of making this game competitive, though. Chris Moore would be my favorite bet to replace Maclin at receiver, but the former Cincinnati wideout is a long shot.
Green Bay vs. Minnesota
Open: 42 O/U, MIN -9
Press time: 41 O/U, MIN -9
What's the case for Baltimore in the previous game is pretty much the case for Minnesota here. Green Bay looks completely toothless at this point, and they match up so poorly that they should probably get put on shutout watch.
So several players should produce for Minnesota, but where will that usage go? Green Bay is more vulnerable to the pass than the run, and you'd generally expect two of Adam Thielen, Stefon Diggs, and Kyle Rudolph to provide useful fantasy returns. But there might not be a great deal of passing volume to go around in a game where Minnesota might be capable of winning without throwing the ball a single time.