This article is part of our NFL Game Previews series.
New England at Buffalo (+14), 44.5 o/u – Monday, 8:15 p.m. EDT
The Story: The Pats have won five straight, but imagine how scary they would be if their offense was intact. Sony Michel's dealing with a knee injury, Gronk is an old man at 29 years old, and Josh Gordon is still nursing his hamstring – although that didn't stop him from posting his first 100-yard game of the year last week. Just so long as Tom Brady is OK, though, the rest is noise. As for the Bills ... look, I know they already have two wins, but if they never score another point again it wouldn't be a huge surprise. Pulling a QB in off the street to start an NFL game turned out not to be such a great idea, and Derek Anderson may not even be healthy enough to make it through a second game, which would force Buffalo to turn back to Nathan Peterman. Injuries in the backfield basically leave them with no plausible path to even 20 points which doesn't involve fluky bounces and defensive scores. The defense is capable of it – they're in the top 10 in turnovers generated, although they haven't kept pace with the pick-prone offense – but against Brady, that's a very narrow path to even keeping this game close, much less pulling off a prime time upset.