Fading Mohamed Salah could be a dangerous strategy Saturday, as Liverpool are by far the biggest favorites on the slate as they host Bournemouth at Anfield.
Swansea City were unable to score at Sheffield Wednesday last week, which means manager Carlos Carvalhal could start Jordan Ayew up front to help Swansea advance in the FA Cup.
Swansea City are the biggest favorites on Tuesday's slate (no, really!), but can fantasy players rely on Jordan Ayew?
Tottenham are the biggest favorites on Saturday's four-game slate, but there's no guarantee Christian Eriksen will get a start given the situation.
Saturday's seven-game slate will be all about how many Manchester City players can fit into fantasy lineups, which opens up a big opportunity in GPPs.
Harry Kane's fantasy floor is a bit higher than he gets credit for, but does that mean fantasy players have to pay up for the Spurs striker Saturday?
Mohamed Salah is one of the most expensive players on Saturday's seven-game slate, but there may not be a hotter player in the Premier League.
James Milner has been a dominant fantasy option of late, but is his rising price worth it Saturday against West Ham?
Manchester City are the biggest favorites on Saturday's six-game slate, but choosing the right attackers won't be easy, especially with the possible return of Sergio Aguero.
Fantasy players are likely to want lots of exposure to Tottenham and Manchester City on Saturday, which means they'll need plenty of value plays to pair with the high-priced attackers.
Manchester United are the biggest favorites on the slate, and Romelu Lukaku is surely to be highly owned in cash games and tournaments because of his goal-scoring odds.
Romelu Lukaku is the top forward option on Saturday's five-game slate, and Kevin Swanson makes the case for fantasy players to pair him with Christian Benteke.
Andrew Laird and Jordan Cooper review their daily fantasy soccer lineup decisions from Gameweek 1 of the Premier League.
DraftKings' first big Premier League slate of the season locks at 10:00 a.m. EDT on Saturday, and RotoWire's Andrew Laird breaks down a few key plays who should help fantasy managers build their lineups.
Manchester City have a number of excellent attacking players, and Kevin Swanson has a few keys to fitting in as many as possible.
Chelsea are the biggest favorites on Saturday's slate, with fantasy managers likely to strongly consider Willian.