The 2016 European Championship kicks off this weekend, and Chris Henne returns with his top picks for DFS contests.
A home match against the porous Sunderland defense vaults Tottenham's Harry Kane to the top of the forwards rankings this week.
After scoring in Arsenal's FA Cup win over Sunderland this past weekend, Olivier Giroud now sports 16 goals in 21 starts this season, and he takes the Best XI captain's armband for Week 21.
After losing 4-0 to Southampton on Boxing Day, Arsenal will try to bounce back at home against Bournemouth, which moves Olivier Giroud to the top of the positional rankings.
The top two goal scorers in the Premier League will face off against each other this weekend when Everton hosts Leicester City, and Romelu Lukaku will make his case for being the top striker this season.
Arsenal is facing yet another injury crisis, but a fit Mesut Ozil continues to pull the strings and heads into this weekend's match against Aston Villa with a league-leading 12 assists.
After exploding in Arsenal's midweek Champions League match against Dinamo Zagreb, Alexis Sanchez takes the top spot in the weekly Premier League rankings.
Manchester City continue to dominate the rankings, with Kevin De Bruyne a unanimous top choice for the midfielders this weekend.
Manchester City are heavy favorites this weekend at home against Newcastle, with four players from the club atop the positional rankings.
The addition of Kevin De Bruyne has vastly improved the already potent Manchester City midfield, but Yaya Toure also garnered two first-place votes in the midfielder rankings this week.
After an excellent debut season in the Premier League, Arsenal's Alexis Sanchez has struggled out of the game this term, and RotoWire's Tate McIntrye argues Alexis is just too expensive to own in most formats.
Manchester City has yet to allow a goal this season, and thanks to his role in their attack, Aleksandar Kolarov grabs the top spot in the weekly defender rankings yet again.
With the summer transfer window finally closed, RotoWire's Premier League contributors updated their rankings to include players that may have moved since the season started, or adjusted those that have looked good (or bad) early on.