Duke
33.0 Pts
Syracuse
27.5 Pts
Saturday September 27, 2025 at 12:00 PM ET
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Moneyline
DraftKings DraftKings
-218
PROBABILITY with vig removed
Duke Blue Devils Win (-218)
65.7%
Syr Orange Win (+180)
34.3%
LINE MOVEMENT
Spread
DraftKings DraftKings
-5.5
PROBABILITY with vig removed
Duke Win By 6+ Pts(-105)
48.9%
Syr Win or Lose By < 6 Pts(-115)
51.1%
LINE MOVEMENT
Over Under
DraftKings DraftKings
60.5
Points
PROBABILITY with vig removed
Over 61 Total Points(-108)
49.6%
Under 61 Total Points(-112)
50.4%
LINE MOVEMENT
Duke
Blue Devils Injury Report
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Syr
Orange Injury Report
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Duke
Blue Devils News
#3 WR
Andrel Anthony: Dead quiet in win
Sep 22nd
Anthony gathered in 0 of 2 targets for zero yards during Saturday's 45-33 victory over North Carolina State.
#4 WR
Sahmir Hagans: Another touchdown in win
Sep 22nd
Hagans reeled in all three targets for 63 yards and one touchdown during Saturday's 45-33 win against North Carolina State.
#2 WR
Cooper Barkate: Finds end zone in win
Sep 22nd
Barkate hauled in 3 of 6 targets for 65 yards and one touchdown during Saturday's 45-33 win versus North Carolina State.
#2 RB
Nate Sheppard: Leads Duke in carries in win
Sep 22nd
Sheppard accrued 14 carries for 61 yards and caught all three targets for 20 yards during Saturday's 45-33 victory against North Carolina State.
#3 RB
Anderson Castle: Huge performance out of nowhere
Sep 22nd
Castle logged 12 carries for 92 yards and three touchdowns and reeled in their only target for 13 yards during Saturday's 45-33 win versus North Carolina State.
#1 QB
Darian Mensah: Another three-touchdown day
Sep 22nd
Mensah was 19-for-28 passing for 269 yards and three touchdowns during Saturday's 45-33 win versus North Carolina State. He also had five rushes for negative two yards.
#1 RB
Jaquez Moore: Taken off injury report
Sep 20th
Moore (undisclosed) isn't listed on Duke's injury report ahead of Saturday's matchup versus NC State.
#1 WR
Que'Sean Brown: Leading receiver in loss
Sep 15th
Brown caught 6 of 9 targets for 81 yards during Saturday's 34-27 defeat to Tulane.
Syr
Orange News
#1 WR
Darrell Gill: Scores on limited receptions
Sep 22nd
Gill reeled in 2 of 5 targets for 41 yards and one touchdown during Saturday's 34-21 victory versus Clemson.
#2 WR
Johntay Cook: Pops in Week 4
Sep 22nd
Cook caught 6 of 12 targets for 113 yards during Saturday's 34-21 win against Clemson.
#3 WR
Justus Ross-Simmons: Rebounds with two scores
Sep 22nd
Ross-Simmons notched five receptions (on 11 targets) for 53 yards and two touchdowns during Saturday's 34-21 victory versus Clemson.
#1 RB
Yasin Willis: Tops 100 yards from scrimmage
Sep 22nd
Willis recorded 18 carries for 94 yards and hauled in 1 of 2 targets for seven yards during Saturday's 34-21 win over Clemson.
#2 RB
Will Nixon: Reverts to secondary role
Sep 22nd
Nixon posted 10 carries for 46 yards and one touchdown and gathered in all three targets for 23 yards during Saturday's 34-21 win over Clemson.
#1 QB
Rickie Collins: Will be starting quarterback
Sep 21st
Collins will be Syracuse's starting quarterback, Matt Zenitz of CBS Sports reports.
#3 QB
Steve Angeli: Out for remainder of season
Sep 21st
Angeli is out for the remainder of Syracuse's 2025 season due to an Achilles injury, Pete Thamel of ESPN.com reports.
#5 TE
Rubin Wasserman: Inactive Week 4
Sep 20th
Wasserman (undisclosed) will not appear in Saturday's game against Clemson.
#6 WR
Emanuel Ross: Off injury report
Sep 20th
Ross is off the injury report and is set to play in Saturday's game at Clemson.
#4 WR
Tyshawn Russell: Ready to roll vs. Clemson
Sep 20th
Russell (undisclosed) is off Syracuse's injury report ahead of Week 4 against Clemson.
#8 WR
Ja'Meer Thomas: Won't play Saturday
Sep 18th
Thomas will not suit up for Saturday's game versus Clemson.
#1 TE
Dan Villari: Slows down in Week 3
Sep 15th
Villari gathered in all four targets for 40 yards during Friday's 66-24 victory versus Colgate.
#10 WR
Darien Williams: Scores in college debut
Sep 15th
Williams gathered in all three targets for 72 yards and one touchdown during Friday's 66-24 victory versus Colgate.
#5 RB
Malachi James: Out for Week 3, maybe longer
Sep 12th
James (undisclosed) is out for Friday's game against Colgate and could be out long-term, Brent Axe of The Syracuse Post-Standard reports.