The NFL Week 6 odds and betting lines highlight what could be the most exciting series of AFC-NFC matchups in the entire 2023 season. Week 6 of the NFL regular season is here, and top online sportsbooks have just unveiled NFL betting odds for all the upcoming games.
The action kicks off with Thursday Night Football, featuring the Kansas City Chiefs, who are strong -10 favorites at home against their AFC West rivals, the Denver Broncos.
Sunday promises a full day of exciting matchups, starting with the undefeated San Francisco 49ers hitting the road to face the Cleveland Browns, who are the underdogs at +5. Meanwhile, the Philadelphia Eagles are the favorites on the road at -6 against the New York Jets.
The week concludes with Sunday Night Football, showcasing the New York Giants as significant underdogs at +15 against the Buffalo Bills. Then, on Monday Night Football, the Los Angeles Chargers will host the Dallas Cowboys, with the Cowboys being favored at -2.
For all the latest odds, point spreads, and more on each of the upcoming NFL games in Week 6 of the regular season, continue reading below.
For a more in-depth look check out the 2023 NFL Schedule.