Kyler Murray headshot

Kyler Murray Injury: Won't start Sunday

Written by RotoWire Staff

Updated on November 5, 2025 at 12:44pm

Arizona head coach Jonathan Gannon announced that Jacoby Brissett will start Sunday's game in Seattle instead of Murray (foot), Darren Urban of the Cardinals' official site reports.

After Monday's 27-17 win over the Cowboys, Gannon suggested that Murray would return to the starting role once fully recovered from a mid-foot sprain that has sidelined him for three straight games. However, John Gambadoro of Arizona Sports 98.7 FM relays that Gannon appeared to do an about-face on those comments a day later during a radio appearance, with the coach noting that he made the decision to go with Brissett as his starter in Week 10 even if Murray was 100 percent healthy. The coach made no declarations on his plans at quarterback beyond Week 10, but if Brissett continues to lead the offense effectively in Seattle, he could retain the No. 1 job. Murray was a limited practice participant in Week 9 prep, and it's unclear how close he might be to fully putting the foot injury behind him. According to Adam Schefter of ESPN, Murray was initially provided estimated recovery timelines ranging from 4-to-8 weeks, but he's already missed the lower end of that range. Gannon also acknowledged that Murray could still be a candidate for injured reserve, despite Murray not being officially ruled out from serving as Brissett's backup or as an emergency No. 3 quarterback in Week 10.

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