2024 Rush/Rec Stats
ATT
84
YDS
420
TD
4
YDS
152
TD
0
2025 Projections
2025 Fantasy Outlook
Few running backs in NFL history come close to the raw athletic ability of Guerendo, who at 6 feet, 220 pounds has blazing speed (4.33 40) and elite explosiveness (41.5-inch vertical, 129-inch broad jump). It's such a shame, then, that Guerendo may be one of the most fragile RB prospects in recent memory. He had horrendous injury luck for all but one of the past six years, at one point in college suffering hamstring tears two years in a row before suffering a Lisfranc injury the third year. In his 2024 rookie year, Guerendo missed time at various points with hamstring, groin and foot injuries, and in the season finale against Arizona he suffered an MCL sprain and ankle sprain in the same leg. As if to make all of this more tormenting, Guerendo has real skill in addition to his ridiculous athleticism - he runs with power and is likely an above-average receiver - but it just isn't clear he can ever stay healthy to realize his upside. For now, Guerendo will compete with August trade acquisition Brian Robinson for the second spot on San Francisco's RB depth chart, behind workhorse Christian McCaffrey. Read Past Outlooks
RANKS
Signed a four-year, $4.72 million contract with the 49ers in May of 2024.
Playing through shoulder inury
Guerendo (shoulder) rushed the ball eight times for 13 yards in Saturday's 30-23 preseason win over the Chargers. He added one reception on one target for one yard.
ANALYSIS
Guerendo started the game with Christian McCaffrey resting and Brian Robinson not yet officially with the team. Per Eric Branch of the San Francisco Chronicle, Guerendo appeared to aggravate the shoulder injury he suffered earlier in camp in the first quarter and was wearing a brace as protection. Positively, he was able to return to the game, so it appears as though he'll be available for San Francisco's Week 1 matchup against Seattle -- albeit with an unclear role.
Guerendo started the game with Christian McCaffrey resting and Brian Robinson not yet officially with the team. Per Eric Branch of the San Francisco Chronicle, Guerendo appeared to aggravate the shoulder injury he suffered earlier in camp in the first quarter and was wearing a brace as protection. Positively, he was able to return to the game, so it appears as though he'll be available for San Francisco's Week 1 matchup against Seattle -- albeit with an unclear role.
NFL Stats
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Fantasy/Red Zone Stats
See red zone opportunities inside the 20, 10 and 5-yard lines along with the percentage of time they converted the opportunity into a touchdown.
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Advanced NFL Stats
How do Isaac Guerendo's 2024 advanced stats compare to other running backs?
This section compares his advanced stats with players at the same position. The bar represents the player's percentile rank. The longer the bar, the better it is for the player.
Broken Tackle %
10.7%Positive Run %
81.0%% Yds After Contact
79.3%Avg Yds After Contact
4.0Rushing TD %
4.8%Touches Per Game
6.2% Snaps w/Touch
45.0%Air Yards Per Game
3.1Air Yards Per Snap
0.23% Team Air Yards
1.2%% Team Targets
3.1%Avg Depth of Target
3.1 YdsCatch Rate
93.8%Drop Rate
0.0%Avg Yds After Catch
7.1% Targeted On Route
16.2%Avg Yds Per Route Run
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2024 NFL Game Log
2024
2024 NFL Game Log
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Snap Distribution / Depth Chart
Snap Counts
Snap %
49ers 2024 RB Snap DistributionLoading Weekly Snap Counts...
Receiving Alignment Breakdown
See where Isaac Guerendo lined up on the field and how he performed at each spot.
Detailed
Grouped
Side
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2024 Isaac Guerendo Split Stats
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Measurables Review
View College Player Page
How do Isaac Guerendo's measurables compare to other running backs?
This section compares his draft workout metrics with players at the same position. The bar represents the player's percentile rank. For example, if the bar is halfway across, then the player falls into the 50th percentile for that metric and it would be considered average.
Height
6' 0"Weight
221 lbs40-Yard Dash
4.33 secShuttle Time
4.15 secCone Drill
6.94 secVertical Jump
41.5 inBroad Jump
129 inHand Length
9.25 inArm Length
30.75 in
2024 Fantasy Outlook
A 4.33 40-yard time and a strong overall performance at the Combine launched Guerendo up draft boards, and the 49ers traded up in the fourth round to make sure they got the 221-pound speedster. Kyle Shanahan's offense is arguably the best in the league for a running back, especially one with game-breaking speed, though Guerendo figures to begin his career behind three-down workhorse Christian McCaffrey and the brittle Elijah Mitchell. Guerendo was never a lead back during his time at Wisconsin and Louisville, but he averaged 6.1 yards on 132 carries for the Cardinals last season and now becomes one of the fastest running backs in the NFL.
More Fantasy News
Facing competition from Robinson
Guerendo may open the season as San Francisco's No. 2 running back even though the team is trading for Brian Robinson, Cam Inman of The San Jose Mercury News reports.
ANALYSIS
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Returns to practice
Guerendo (shoulder) participated in Tuesday's training camp practice, Nick Wagoner of ESPN.com reports.
ANALYSIS
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Out for a few weeks
San Francisco coach Kyle Shanahan said Monday that Guerendo (shoulder) is expected to miss a couple weeks, Matt Maiocco of NBC Sports Bay Area reports.
ANALYSIS
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Exits practice with apparent injury
Guerendo had an early departure from practice Saturday due to an apparent shoulder injury, Jennifer Lee Chan of NBC Sports Bay Area reports.
ANALYSIS
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On field for OTAs
Guerendo (knee/ankle) was an active participant at voluntary OTAs, per the 49ers' official site.
ANALYSIS
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Latest Fantasy Rumors
Significant competition added
Guerendo is now joined on the 49ers' running back depth chart by Brian Robinson, who was traded from the Commanders to San Francisco on Friday, as reported by John Keim and Adam Schefter of ESPN.
ANALYSIS
Guerendo showed plenty or promise with his opportunities during his rookie campaign, averaging 5.0 yards per carry on 84 rush attempts while adding four rushing touchdowns. However, the second-year back has a fairly lengthy injury history dating back to college and just overcame a shoulder injury, which may have played a role in the team's decision to acquire another starting-quality running back in Robinson. Guerendo may still have a leg up on the No. 2 job to begin the season due to Robinson's unfamiliarity with the playbook, but any absences on the part of the former could lead to some longer-term reordering of the depth chart behind McCaffrey.
Guerendo showed plenty or promise with his opportunities during his rookie campaign, averaging 5.0 yards per carry on 84 rush attempts while adding four rushing touchdowns. However, the second-year back has a fairly lengthy injury history dating back to college and just overcame a shoulder injury, which may have played a role in the team's decision to acquire another starting-quality running back in Robinson. Guerendo may still have a leg up on the No. 2 job to begin the season due to Robinson's unfamiliarity with the playbook, but any absences on the part of the former could lead to some longer-term reordering of the depth chart behind McCaffrey.