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Best Bets for Iowa State Cyclones vs. Cincinnati Bearcats | Cincinnati Bearcats Moneyline (-120)
The 14th-ranked Iowa State Cyclones will play their second true road game of the season against a 3-1 Cincinnati Bearcats team at 12 p.m. ET. The Bearcats just shocked the Kansas Jayhawks with a 37-34 win in regulation in Lawrence, so now, Cincinnati is riding a ton of momentum into its third home game of 2025.
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Oddsmakers are laying -1.5 with Cincinnati, making them a favorite on the point spread against the undefeated Cyclones. The Bearcats' lone loss came in Week 1, when they lost 20-17 on a neutral site field against Nebraska.
Cincinnati has logged over 330 passing yards in three straight games, including over 600 yards of offense against the Jayhawks in Week 5. Iowa State's defense ranks 18th in the nation, so Bearcats QB Brendan Sorsby will have a big test facing the Cyclones' secondary.
Let's ride the hot hand in this matchup, especially with Iowa State's offense only logging two passing touchdowns in its past three games played. Bet on Cincinnati to win outright on the moneyline in their biggest game of 2025 at -120.
Best Bets for Iowa State Cyclones vs. Cincinnati Bearcats | Iowa State Cyclones Under 26.5 Total Points (-105)
While the Bearcats' offense has been the better unit, don't sleep on Cincinnati's defense. They are ranked top-40 in the country for points allowed per game, with only Kansas managing to score more than 20 points this season.
Iowa State's offense is good but not great, averaging under 3.8 YPC and committing a turnover in four of five games. The Cyclones have scored 24 or fewer points against Kansas State, Iowa, and Arkansas State.
The Cyclones are playing in a hostile environment and face a lot of pressure to keep their undefeated record intact. Let's bet on Iowa State to finish with under 26.5 total points for the fourth game in 2025.
Best Bets for Iowa State Cyclones vs. Cincinnati Bearcats | Cincinnati 1Q Moneyline (-130)
We're going to grab some action in the 1st Quarter betting market and double down on the Cincinnati Bearcats. They are a -130 moneyline favorite to win the 1st quarter, which the Bearcats have done in three of four games, while tying Kansas 7-7 in Week 5.
Iowa State is 5-0 SU in the 1st quarter in 2025. This streak will be snapped on the road against Cincinnati on Saturday, with the Bearcats' stingy run defense and high-octane passing attack leading to an early lead against the Cyclones.
Bet on Cincinnati's 1st Quarter Moneyline at -130.
Iowa State Cyclones vs. Cincinnati Bearcats Picks
- Cincinnati Bearcats Moneyline (-120)
- Iowa State Cyclones TTU 26.5 (-105)
- Cincinnati Bearcats 1Q Moneyline (-130)
Best Events to Use the Caesars Sportsbook Promo Code ROTO20X For on October 4th
- College Football: Miami (FL) Hurricanes vs. Florida State Seminoles. Carson Beck and the Hurricanes are -4.5 point road favorites against Tommy Castellanos and the Seminoles' top-ranked scoring offense. Point total 53.5.
- College Football: Minnesota Golden Gophers vs. Ohio State Buckeyes. The No. 1-ranked team in the country, Ohio State, is laying -23.5 at home against a 3-1 Minnesota team. Point total set to 44.5.
- College Football: Mississippi State Bulldogs vs. Texas A&M Aggies. Mississippi State is a +14.0 point road underdog against No. 6 Texas A&M in prime time with a 55.5 point total.
- MLB: All four ALDS and NLDS Game 1 matchups get underway. Host teams include the Toronto Blue Jays, Seattle Mariners, Milwaukee Brewers, and Philadelphia Phillies.
