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MORE: Best sports betting promos
Best Bets for CFB Week 6 Friday Games
Best Bets for Charlotte at South Florida | South Florida -27.5 (-110)
After getting dismantled by Miami, we saw USF take care of business against South Carolina State (63-14) before getting a bye week. That's essentially a one-and-a-half-week break heading into tonight's game.
QB Byrum Brown is one of the top signal-callers in college football, and he will be on full display tonight against a Charlotte team that already has three double-digit losses this season. USF definitely has the firepower to blow out Charlotte, and the extra rest means they've been waiting a while to be unleashed now.
Best Bets for West Virginia-BYU | BYU -19.5
West Virginia has been outscored 89-24 over their last two games, and now they're heading into one of the toughest environments in college football. No thanks!
Meanwhile, BYU has taken care of business against inferior competition this season. Prior to squeaking by Colorado (24-21), BYU had outscored its prior three opponents by the score of 130-16.
CFB Week 6 Friday Picks
- South Florida -27.5 (-110)
- BYU -19.5 (-110)
Best Events to Use the BetMGM Bonus Code for Friday, October 3, 2025
- College Football: Charlotte at South Florida, 7 p.m. ET | USF looks to pile it on against a Charlotte team that has struggled to score points this season. Bet on USF's team total tonight in the props section at one of the top college football betting sites.
- College Football: West Virginia at (23) BYU, 10:30 p.m. ET | Out West, we'll cap off the Friday night CFB slate with BYU hosting WVU. Get started tonight with one of the top college football betting promos.
- WNBA Finals: Game 1 – Phoenix Mercury at Las Vegas Aces, 8 p.m. ET | Before the NBA tips off in a couple of weeks, we have a title to settle. This battle will be set in the West, as it's Phoenix-Las Vegas going for all the marbles.
