Napoli need a win and help elsewhere to qualify for the knockout rounds of the Champions League, and they'll look for Lorenzo Insigne to make a big impact.
Monaco aren't the biggest favorites on Tuesday's eight-game Champions League slate, but bookmakers are still expecting Radamel Falcao to have a big impact.
Radamel Falcao has 11 goals in seven Ligue 1 matches this season, and he'll look to bag his first one in the Champions League Tuesday against Porto.
Cristiano Ronaldo hasn't been able to play during Real Madrid's La Liga matches due to suspension, and he'll look to take out his frustrations on Apoel Nicosia on Wednesday.