Kei Kamara is tied with Sebastian Giovinco for the MLS goal lead, but the Crew striker is unavailable this weekend due to yellow card accumulation.
Orlando City continues to fight for a playoff spot, but they'll face off against New York City FC this weekend without Kaka, who is suspended for the match.
Sebastian Giovinco is away on international duty, leaving a big void to fill for TFC and fantasy players during Wednesday's three-game MLS slate.
Matt Miazga is away on international duty to try and help the U.S. qualify for the 2016 Olympics, and he is one of a number of players who will miss out on MLS' two-game Wednesday slate
RotoWire's D.J. Trainor breaks down all the injury news ahead of this weekend's slate of MLS matches, including Javier Morales, who is questionable with a hip injury.
Kaka has missed two games recently due to injury, but he could return to face the Red Bulls on Friday. RotoWire's D.J. Trainor breaks down all the MLS injury news heading into the weekend.
Sebastian Giovinco was slated to play for Italy over the international break, which MLS plays through, but an adductor injury will keep him on the sidelines.
The Sounders could desperately use Clint Dempsey back in the lineup to pair with Obafemi Martins, but he remains questionable because of a hamstring injury.
Mauro Diaz is questionable for Saturday's match at Vancouver because of a quad injury that held him out last weekend. D.J. Trainor breaks down the other injury news heading into the weekend.
Obafemi Martins looks set to return for the Sounders this weekend, but he could be without strike partner Clint Dempsey.
Sebastian Giovinco was unable to play in the MLS All-Star Game because of a heel injury, but he has a shot at getting back on the pitch for Toronto FC on Saturday.
The Sounders could be getting a number of players back from the Gold Cup this weekend, but Obafemi Martins remains sidelined with a groin injury.
Jozy Altidore has returned to Toronto FC after being dropped from the USMNT Gold Cup roster, but a number of key MLS players won't play this weekend.