Van Persie has been ruled out for four-to-six weeks after suffering a sprained knee during Wednesday's Champions League win over Olympiakos, BBC Sport reports.

Manager David Moyes said the first scan on van Persie's knee was inconclusive, leading to some optimism that the injury wasn't too serious. A second scan confirmed the tough news, with United needing all the help they can get to possibly make a run at a top-four finish. That seems all but over now, although there is a slight chance van Persie will be able to play in the Champions League quarterfinals against Bayern Munich.

Van Persie, who had to be stretchered off of Wednesday's Champions League match against Olympiakos, is considered an injury doubt for Saturday's Premier League match against West Ham, but should be cleared to play in the Manchester derby on Tuesday, the Daily Mail reports.

The injury looked bad at first, but manager David Moyes said after that he did not consider it serious. Van Persie isn't exactly known for being a durable player, so it wouldn't be surprising at all if he was held out of Saturday's match in order to get as fit as possible to face Manchester City.

Van Persie, who netted a hat trick in Wednesday's Champions League match against Olympiakos, was carried off on a stretcher after picking up a knock near the end of the game, the Daily Mail reports. Manager David Moyes said afterward that "It doesn't look that bad. It may have been just a knee in the back."

Van Persie hasn't exactly been the fittest player this season, or for much of his whole career, so any knock like this should be taken seriously. It comes at a tough time for fantasy players, as Manchester United have two gameweek 31 matches, but van Persie's value will obviously drop versus other two-match strikers if he's not able to feature in both games (Saturday at West Ham, Tuesday against Manchester City).

Van Persie took a step to correct swirling rumors that he is unhappy at Manchester United and said that he would even be willing to extend his current contract, reports Sky Sports.

The subject of Van Persie being settled and content has been a major storyline with some speculation that the player would try to leave the club this summer. He worked to set the record straight by saying publicly that he is happy at United and with manager David Moyes. Van Persie has two years still remaining on his current contract.

Van Persie assisted on Phil Jones' 34th minute goal during Manchester United's 3-0 win over West Brom on Saturday.

Van Persie's low free kick was headed in by Jones to open the scoring Saturday. The Dutch striker has been injury-bitten this year, but he has still managed to score 11 goals and assist on three others in 17 Premier League appearances.

Van Persie apologized to his teammates and said he was not criticizing them in his post match comments following defeat to Olympiakos on Tuesday, reports the Mirror.

Van Persie said that his comments were focused on his game, and were not critical of his teammates, but rather his own play on Tuesday. The comments fueled speculation that the striker may seek to leave Manchester United this summer.

Van Persie criticized his Manchester United teammates following the team's defeat to Olympiacos on Tuesday, saying they occupy the space he wants to play in, reports the Daily Mail.

Van Persie had a few chances on Tuesday night, but did seem to be thwarted by his own teammates being too close, or in the way at times. He added that he needs to adjust his runs based on his teammates and it shrinks the zone in which he is able to work.