San Francisco 49ers vs Denver Broncos Odds, Week 2, 2025

#5 WR

Jordan Watkins: Paces pass catchers in defeat

Aug 9th

Watkins brought in three of six targets for 56 yards in the 49ers' 30-9 preseason loss to the Broncos on Saturday night.

#5 RB

Patrick Taylor: Scores rushing touchdown Saturday

Aug 9th

Taylor rushed five times for seven yards and a touchdown and secured his only target for four yards in the 49ers' 30-9 preseason loss to the Broncos on Saturday night.

#6 WR

Demarcus Robinson: Two catches in team debut

Aug 9th

Robinson brought in both targets for 20 yards in the 49ers' 30-9 preseason loss to the Broncos on Saturday night.

#3 RDE

Robert Beal: Sustains groin injury

Aug 9th

San Francisco head coach Kyle Shanahan said Saturday that Beal (groin) suffered an injury late during the team's 30-9 preseason loss to Denver, David Lombardi of SFStandard.com reports.

#2 FS

Marques Sigle: Initially injury diagnosis hopeful

Aug 9th

San Francisco head coach Kyle Shanahan said Saturday that Sigle will still undergo testing but that initial indications are that he's avoided a serious knee injury, Nick Wagoner of ESPN.com reports.

#1 SCB

Upton Stout: Dealing with calf tightness

Aug 9th

San Francisco head coach Kyle Shanahan said Stout (calf) did not suit up for Saturday's 30-9 preseason loss to the Broncos due to calf tightness, Rich Cimini of ESPN.com reports.

#1 TE

George Kittle: Not expected to play Saturday

Aug 9th

Kittle isn't warming up ahead of Saturday's preseason game against the Broncos and isn't slated to play, Nick Wagoner of ESPN.com reports.

#1 QB

Brock Purdy: Not slated to play Saturday

Aug 9th

Purdy didn't warm up and isn't likely to play in Saturday's preseason game against Denver, Nick Wagoner of ESPN.com reports.

#1 RB

Christian McCaffrey: Not on track to play Saturday

Aug 9th

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report.

#5 QB

Tanner Mordecai: Back in Bay Area

Aug 8th

The 49ers signed Mordecai to a contract Friday, Cam Inman of The San Jose Mercury News reports.

#1 LDE

Mykel Williams: Hurts knee Thursday

Aug 7th

Williams is unlikely to suit up for Saturday's preseason game against Denver after exiting Thursday's practice due to a knee injury, Matt Barrows of The Athletic reports.

#4 RB

Jordan James: Breaks finger, out a few weeks

Aug 7th

San Francisco head coach Kyle Shanahan said Thursday that James will miss a couple weeks due to a broken finger, Cam Inman of The San Jose Mercury News reports.

#7 WR

Brandon Aiyuk: Not expected for Week 1

Aug 7th

San Francisco GM John Lynch said Thursday he "doesn't think" Aiyuk (ACL), who remains on the active/PUP list, will be cleared to play Week 1, Cam Inman of The San Jose Mercury News reports.

#2 WR

Ricky Pearsall: Standing out at practice

Aug 6th

Pearsall has impressed in recent practices and was a clear standout on offense Tuesday, connecting with quarterback Brock Purdy on five targets, Nick Wagoner of ESPN reports.

#2 RDE

Sam Okuayinonu: Misses practice Monday

Aug 4th

Okuayinonu (groin) sat out of practice Monday, Eric Branch of The San Francisco Chronicle reports.

#1 SS

Ji'Ayir Brown: Sits out of practice Monday

Aug 4th

Brown (ankle) did not participate in practice Monday, Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 FB

Kyle Juszczyk: Misses practice Monday

Aug 4th

Juszczyk (Achilles) did not participate in practice Monday, Jennifer Lee Chan of NBC Sports Bay Area reports.

#4 LDT

Kevin Givens: Out with pectoral injury

Aug 4th

Givens is expected to miss the start of the 2025 regular season due to a pectoral injury, David Lombardi of SFStandard.com reports.

#1 WR

Jauan Jennings: Sidelined by calf again

Aug 4th

Jennings (calf) isn't practicing Monday, Jennifer Lee Chan of NBC Sports Bay Area reports.

#3 RB

Isaac Guerendo: Out for a few weeks

Aug 4th

San Francisco coach Kyle Shanahan said Monday that Guerendo (shoulder) is expected to miss a couple weeks, Matt Maiocco of NBC Sports Bay Area reports.

#1 K

Jake Moody: Appears to win job

Aug 4th

Moody is the only kicker on San Francisco's roster after the team released Greg Joseph on Monday, Matt Maiocco of NBC Sports Bay Area reports.

#1 LG

Ben Bartch: In line to start at LG

Aug 4th

Offensive line coach Chris Foerster declared Sunday that the starting left guard spot is "Bartch's job to lose," Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 RCB

Deommodore Lenoir: Missing time with hip injury

Jul 31st

Lenoir is expected to miss the next few practices with a hip injury, David Lombardi of SFStandard.com reports.

#4 QB

Carter Bradley: Joins San Francisco

Jul 31st

The 49ers signed Bradley to a one-year contract Thursday, Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 RT

Colton McKivitz: Returns from injury

Jul 31st

McKivitz (undisclosed) is fully healthy and participated in training camp Wednesday, Mike Maynard reports.

#2 RCB

Darrell Luter: Participating in training camp

Jul 31st

Luter (pelvis) has been participating in training camp, Grant Cohn of Sports Illustrated reports.

#2 DT2

Alfred Collins: Back at training camp

Jul 30th

Collins (calf) has fully participated in practices during the 49ers' first week of training camp, Mike Maynard of The Sporting News reports.

#3 WR

Russell Gage: Healthy start to camp

Jul 29th

Gage made an athletic grab during Tuesday's padded practice session, Matt Barrows of The Athletic reports.

#4 RDE

Tarron Jackson: Placed on IR

Jul 29th

The 49ers placed Jackson (undisclosed) on injured reserve Tuesday.

#1 WLB

Dee Winters: Competing for starting role in camp

Jul 27th

Winters drew praise from a star teammate at the start of training camp as the linebacker prepares to compete for a starting role in 2025, Vic Tafur of The Athletic reports.

#8 WR

Jacob Cowing: Hopeful to return in 2-3 weeks

Jul 27th

San Francisco coach Kyle Shanahan said Sunday that he's hopeful Cowing (hamstring) will be back by the week of Aug. 11 for joint practices with the Raiders, David Lombardi of SFStandard.com reports.

#1 LCB

Renardo Green: Will be out several weeks

Jul 27th

Green (hamstring) is expected to be sidelined for the next several weeks, David Lombardi of SFStandard.com reports.