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Bears vs Bills Odds, Lines, Spreads & Totals 2021

Bills
Bears
Saturday August 21, 2021 at 1:00 PM ET
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BUF
Bills Injury Report
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CHI
Bears Injury Report
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BUF
Bills Lineup
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CHI
Bears Lineup
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BUF
Bills News
#1 TE
Dawson Knox: Targeted twice
Aug 21st
Knox recorded one reception on two targets for 10 yards in Saturday's preseason game against the Bears.
#2 RB
Zack Moss: Handles four carries
Aug 21st
Moss carried the ball four times for 21 yards in Saturday's preseason game against the Bears.
#2 RB
Devin Singletary: Finds end zone again
Aug 21st
Singletary carried the ball twice for 21 yards and a touchdown and added one reception for five yards in Saturday's preseason game against Chicago.
#1 NT
Harrison Phillips: Downgraded to out
Aug 21st
Phillips (knee) will not return to Saturday's preseason game against the Bears.
#11 WR
Isaiah Hodgins: Not playing Saturday
Aug 21st
Hodgins (knee) will not play Saturday against the Bears, Jay Skurski of The Buffalo News reports.
#2 QB
Mitchell Trubisky: Busy weekend ahead
Aug 19th
Trubisky should get a lot of playing time in Saturday's preseason game against the Bears, Adam Hoge of NBC Sports Chicago reports.
#1 WR
Stefon Diggs: Out for Saturday
Aug 19th
Diggs (knee) could return to practice soon but won't play in Saturday's preseason game against Chicago, Matthew Fairburn of The Athletic reports.
#1 QB
Josh Allen: Won't play this weekend
Aug 19th
Allen won't play in Saturday's preseason game against Chicago, Matt Parrino of syracuse.com reports.
#1 LT
Dion Dawkins: Reveals problems with COVID
Aug 17th
Dawkins, who was activated off the reserve/COVID-19 list last week, revealed Tuesday that his bout with the virus was serious and he ended up hospitalized for four days, Dante Lasting of the Bills' official site reports.
#1 WLB
Matt Milano: Suffers mouth injury
Aug 9th
Milano left Monday's practice due to a mouth injury, Maddy Glab of the Bills' official site reports.
CHI
Bears News
#2 QB
Andy Dalton: Nagy confirms starting Week 1 role
Aug 21st
Coach Matt Nagy said Dalton will start against the Rams in Week 1, ESPN's Adam Schefter reports.
#2 RB
David Montgomery: Sits out second preseason game
Aug 21st
Montgomery did not play in Saturday's preseason game against the Bills, Larry Mayer of the Bears' official site reports.
#2 RB
Khalil Herbert: Finds end zone
Aug 21st
Herbert rushed three times for 15 yards and a touchdown while adding a three-yard reception in the Bears' 41-15 preseason loss to the Bills on Saturday.
#1 QB
Justin Fields: Less impressive in second game
Aug 21st
Fields completed nine of his 19 pass attempts for 80 yards and no touchdowns or interceptions in Saturday's preseason game against the Bills. He also chipped in 46 yards on the ground.
#2 LG
Teven Jenkins: Undergoes back surgery
Aug 21st
Jenkins (back) has undergone successful surgery, and the Bears hope he will be able to return sometime this season, Larry Mayer of the Bears' official site reports.
#1 TE
Cole Kmet: Not in uniform Saturday
Aug 21st
Kmet (hamstring) wasn't in uniform for Saturday's preseason game against the Bills, Brad Biggs of the Chicago Tribune reports.
#2 DT2
Eddie Goldman: Dealing with back injury
Aug 18th
Goldman will not practice Wednesday due to a back injury, Adam Hoge of NBC Sports Chicago reports.
#1 LG
James Daniels: Returns to practice Wednesday
Aug 18th
Daniels (quadriceps) resumed practicing Wednesday, Dan Wiederer of the Chicago Tribune reports.
#1 LILB
Roquan Smith: Returns to practice
Aug 18th
Smith (groin) returned to practice Wednesday, Dan Wiederer of the Chicago Tribune reports.
#2 SCB
Artie Burns: Present at practice
Aug 16th
Burns (knee) is practicing Monday, Larry Mayer of the Bears' official site reports.
#2 LG
Elijah Wilkinson: Back from COVID list
Aug 11th
The Bears activated Wilkinson (undisclosed) from the reserve/COVID-19 list Monday.