Here are Week 1's results:
| Anderson: Pick up John Buck ($1), drop John Bowker |
| High-A West Madison: Pick up Santiago Casilla ($2), drop Tom Gorzelanny (Erickson: $3 - ineligible bid, because of a duplicative drop) (East Coast Bias: $1) (Liss and Shoe's Dynasty: $1) |
| Tuffy's Goats: Pick up Jose Contreras ($3), drop Tyler Walker |
| Erickson: Pick up Kevin Correia ($2), drop Fernando Perez |
| Liss and Shoe's Dynasty: Pick up Chris Coste ($1), drop J.R. Towles |
| Browns: Pick up Scott Downs ($7), drop Brendan Harris (Erickson: $5) (High-A West Madison: $3) (Liss and Shoe's Dynasty: $1) |
| Frozen Ropes: Pick up Livan Hernandez ($3), drop Scott Podsednik |
| Liss and Shoe's Dynasty: Pick up Mark Loretta ($1), drop Alberto Callaspo |
| I Drink Your Milkshake: Pick up Ryan Madson ($2), drop LaTroy Hawkins (Erickson: $1) |
| I Drink Your Milkshake: Pick up Shairon Martis ($8), drop Kevin Frandsen |
| Tropic Thunders: Pick up Gary Matthews ($4), drop Gregor Blanco |
| Gus Ballskin: Pick up Ross Ohlendorf ($8), drop Roy Corcoran (Tuffy's Goats: $3) (Casale Industries: $1) |
| Sheehan: Pick up Tony Pena ($4), drop Ramon Vazquez |
| Erickson: Pick up Edwar Ramirez ($1), drop Mark Lowe |
| Gus Ballskin: Pick up Mike Redmond ($11), drop Aaron Miles (Tuffy's Goats: $1) (Liss and Shoe's Dynasty: $1) (High-A West Madison: $1) |
| Casale Industries: Pick up Ricky Romero ($3), drop Eric Patterson (Erickson: $2) (High-A West Madison: $1) (Browns: $1) |
| Erickson: Pick up Dewayne Wise ($5), drop Melky Cabrera (Frozen Ropes: $4) (Tuffy's Goats: $3) (Liss and Shoe's Dynasty: $2) |