Colin Kaepernick leads the 49ers into St. Louis in an NFC West showdown on Monday Night Football.
C.J. Spiller's squad is the only unanimous pick, getting three at home against the Patriots this week.
Backing the Seahawks at home.
Doug Martin and the Bucs take on a Ravens defense strong against the run
Matt Ryan is a much better quarterback at home.
Detroit's Calvin Johnson has been largely ineffective the last two games, and he may be held out until his ankle improves.
Julio Jones has a ticket to the Bears-Falcons carnival this weekend. Do you?
Also, Brandin Cooks despite heavy targets is not living up to the preseason hype.
New Orleans' sputtering offense might be missing Jimmy Graham even after their bye
RotoWire's Josh Collacchi recommends going heavy on Giants in your Week 6 lineups on Fantasy Aces.
The Saints aren't getting explosive plays downfield like they used to get so often, particularly at home, and that's causing all sorts of problems.
Skepticism of Austin Davis should be at a minimum after consecutive big weeks in a pass-happy Rams offense.
The Cards are down to their third-string quarterback, and Carson Palmer could be done for the season
Danny Trevathan missed the first three games of 2014 due to a preseason leg fracture, but he's set to make his 2014 debut against the Cardinals on Sunday.
Who wins the NFC South?
DFS veteran Nir Elitzur looks at the over/under lines to aid in your lineup selection process in weekly salary cap contests.
RotoWire's Ben Slocum looks at ownership levels of FanDuel's Thursday night contests to highlight which players to target and fade for this weekend.
RotoWire's Michael Rathburn focuses on cash games and explores how to build the best lineup for head-to-head and 50/50 contests.