Boston Scott may be back atop the depth chart after the latest round of injuries in the Philadelphia backfield.
Chuba Hubbard didn't get many carries in Sunday's blowout loss, but it looks like he'll have a second run in the lead role with Christian McCaffrey ruled out for the season.
With Justin Herbert under center and a defensive savant as head coach, the Chargers will look to move up the pecking order in an AFC dominated by the division rival Chiefs the past few seasons.
A slew of big names litter the Week 2 injury report, and Juan Carlos Blanco has the latest for you on who's trending toward starting or sitting as of early Sunday morning.