
As perhaps the AFC North's most complete team, the Colts boast the reigning rushing champ in Jonathan Taylor behind a top-10 offensive line. Beyond Taylor, Michael Pittman represents the biggest fantasy asset.

In the wake of Philip Rivers' retirement, the Colts have decided to give Carson Wentz a second chance. But Indy's offense nonetheless revolves around second-year running back Jonathan Taylor.

Michael Gallup may have been a fantasy bust in 2020, but his late-season usage and production suggests a 1,000-yard season could be around the corner in 2021.

Even though he faces a tough Colts defense Thursday night, fantasy players are still likely to flock to Derrick Henry in cash games and GPPs.

Jakobi Meyers has become the focal point of New England's passing game, while other young wideouts like Preston Williams, Michael Pittman and Denzel Mims are hoping to do the same for their respective teams.