Darrell Henderson finds himself back in the lead role with Cam Akers potentially done in Los Angeles, while Kenyan Drake could benefit in Baltimore if J.K. Dobbins has issues with his knee.
Chuba Hubbard didn't get many carries in Sunday's blowout loss, but it looks like he'll have a second run in the lead role with Christian McCaffrey ruled out for the season.
Dan Marcus goes deep into the free-agent pool to find upside adds who could pay off down the road, if not this week.
Josh Allen finally put it all together for the Bills in 2020 en route to a division title and appearance in the AFC Championship Game. They'll look to take the next step this season.
Josh Allen has been a fantasy star this season, and RotoWire's Andrew Laird is expecting him to be extremely popular on Monday night's slate.
Chase Edmonds supposedly was dealing with an ankle injury, yet finished Sunday's win over the Eagles with more carries, yards and snaps than Kenyan Drake.
Jerry Donabedian estimates Week 1 backfield usage for every team, expecting a large workload for James Conner and possibly a three-down role for Derrick Henry.
Devin Singletary provided Buffalo a spark during his exciting rookie year, but the new back in town is a bigger threat than Frank Gore was. Also looking at Minnesota RBs and Detroit slot WRs.
The Brandin Cooks trade has mostly been discussed from the Texans' perspective, but the biggest fantasy impact could be a career high in targets for Robert Woods.
Jerry Donabedian breaks down some of the backfields that experienced offseason turmoil, starting with both Los Angeles teams.
T.J Hockenson has emerged as one of the best values in early fantasy drafts, often lasting until the 10th or 11th round despite having all the tools for a second-year breakout.
Jerry Donabedian breaks down all the action from Week 17, hoping to find an edge for DFS and dynasty leagues.
Alvin Kamara is the only rock solid player at running back, while the tight end position is deeper than ever.
The NFL free agency process can feel like a whirlwind, so look here for an up to date one-stop inventory.
Without Andrew Luck against the Rams, T.Y. Hilton's weekly ranking takes a pretty big hit in Week 1.
Erik Siegrist previews the Monday Night matchup as Ryan Mathews leads the Eagles into Chicago for date against the Bears.
Andrew Fiorentino surveys the league for the fallout from the first week of preseason games, including a look at the backfield in Oakland where Latavius Murray might feeling heat.
David Soda breaks down a young and rising Raiders squad, hungry to return to postseason glory.