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Texans vs Bills Odds, Lines, Spreads & Totals 2025

Bills
25.0 Pts
Texans
21.5 Pts
Thursday November 20, 2025 at 8:15 PM ET
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BUF
Bills Injury Report
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HOU
Texans Injury Report
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BUF
Bills Lineup
Inactives
    None reported yet.
HOU
Texans Lineup
Inactives
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BUF
Bills News
#3 LDT
DeWayne Carter: Has torn Achilles
Aug 31st
Carter tore his Achilles tendon and will miss the entire 2025 season, NFL reporter Jordan Schultz reports.
#3 SCB
Brandon Codrington: Set to serve as return ace
Aug 29th
Codrington is set to serve as the Bills' return man on kickoffs and punts following the team's roster cuts this week, Chris Brown of the Bills' official site reports.
#1 LCB
Tre'Davious White: Question mark for Week 1
Aug 28th
White, who suffered a lower-leg injury during last Thursday's practice, has yet to return to the practice field and his status remains unknown for the Bills' season opener against the Ravens, Maddy Glab of the Bills' official site reports.
#4 FS
Wande Owens: Reverts to IR
Aug 27th
Owens (undisclosed) reverted to the Bills' injured reserve list Wednesday, Alaina Getzenberg of ESPN.com reports.
#2 RT
Tylan Grable: Placed on IR, designated to return
Aug 27th
Grable (concussion) was placed on injured reserve with a designation to return Tuesday.
#5 WR
Curtis Samuel: Makes the grade
Aug 27th
Samuel (hamstring/illness) has made the Bills' initial 53-man roster.
#1 WR
Khalil Shakir: Resumes practicing
Aug 27th
Shakir (ankle) is participating in Wednesday's practice, Katherine Fitzgerald of The Buffalo News reports
#6 WR
Tyrell Shavers: Makes initial roster
Aug 27th
Shavers has made the Bills' initial 53-man roster.
#2 C
Sedrick Van Pran-Granger: Activated from PUP list
Aug 26th
Van Pran-Granger (undisclosed) was activated from the active/PUP list by Buffalo on Tuesday, Chris Brown of the Bills' Radio Network reports.
#3 FS
Sam Franklin: Signs with Buffalo
Aug 26th
The Bills signed Franklin on Tuesday, Aaron Wilson of KPRC 2 Houston reports.
#3 LCB
Maxwell Hairston: Will miss at least four games
Aug 26th
Hairston (knee) was placed on injured reserve Tuesday.
#1 P
Brad Robbins: Active in preseason finale
Aug 24th
Robbins (illness) was active for the Bills' 23-19 preseason win over the Buccaneers on Saturday.
#1 K
Tyler Bass: Busy night in preseason debut
Aug 23rd
Bass converted three of four field-goal attempts and made both extra-point tries in the Bills' 23-19 preseason win over the Buccaneers on Saturday night.
#3 TE
Jackson Hawes: One catch in preseason finale
Aug 23rd
Hawes brought in his only target for eight yards in the Bills' 23-19 preseason win over the Buccaneers on Saturday night.
#4 WR
Elijah Moore: Three catches in preseason finale
Aug 23rd
Moore brought in three of four targets for eight yards in the Bills' 23-19 preseason win over the Buccaneers on Saturday night.
#1 QB
Josh Allen: Won't play this preseason
Aug 21st
Allen won't play in Saturday's preseason game against Tampa Bay, Chris Brown of the Bills Radio Network reports.
HOU
Texans News
#1 FS
C.J. Gardner-Johnson: On track for Week 1
Sep 1st
Head coach DeMeco Ryans told reporters Monday that Gardner-Johnson (knee) is on track to play in Houston's Week 1 matchup against the Rams, Jonathan M. Alexander of the Houston Chronicle reports.
#3 LDE
Denico Autry: Sidelined to begin season
Aug 27th
Autry (knee) was placed on the reserve/PUP list Tuesday.
#6 RB
Joe Mixon: GM noncommittal on return in 2025
Aug 27th
Texans general manager Nick Caserio declined to answer in the affirmative when asked Wednesday whether Mixon (foot/ankle) will suit up this season, DJ Bien-Aime of ESPN reports.
#2 SCB
Alijah Huzzie: Starting season on NFI list
Aug 27th
Huzzie (undisclosed) was placed on the reserve/non-football injury list Tuesday.
#2 SS
Jaylen Reed: Placed on IR, designated to return
Aug 26th
Reed (ankle) was placed on injured reserve with a designation to return Tuesday.
#4 TE
Irv Smith: Placed on season-ending IR
Aug 26th
The Texans placed Smith (ankle) on injured reserve Tuesday.
#8 WR
Tank Dell: Moved to reserve/PUP list
Aug 26th
The Texans placed Dell (knee) on the reserve/PUP list Tuesday.
#3 FS
Jimmie Ward: Placed on exempt list
Aug 26th
The Texans placed Ward (undisclosed) on the Commissioner Exempt List on Tuesday, Tom Pelissero of NFL Network reports.
#1 RB
Nick Chubb: In line for early-season role
Aug 25th
With Joe Mixon (foot/ankle) slated to begin the season on the reserve/non-football injury list, Chubb appears to be in line for an expanded role.
#5 WR
Xavier Hutchinson: Expected to earn roster spot
Aug 25th
Hutchinson is on the Texans' initial 53-man roster projection, per DJ Bien-Aime of ESPN.com.
#4 RB
Dare Ogunbowale: Projected for 53-man
Aug 25th
Ogunbowale is expected to earn a roster spot in the initial 53-man roster projection compiled by DJ Bien-Aime of ESPN.com.
#5 RB
British Brooks: On roster bubble
Aug 25th
Brooks is one of five running backs projected to make the initial 53-man roster, per DJ Bein-Aime of ESPN.com.
#1 ROLB
Christian Harris: Suits up Saturday
Aug 24th
Harris recorded two tackles in Saturday's 26-7 preseason win over the Lions.
#3 WR
Jayden Higgins: Two grabs in Saturday's win
Aug 23rd
Higgins caught both his targets for 18 yards in Saturday's 26-7 preseason win over the Lions.
#3 RB
Woody Marks: Hits paydirt in preseason finale
Aug 23rd
Marks carried the ball six times for 19 yards and a touchdown and caught all three of his targets for 20 yards in Saturday's 26-7 preseason win over the Lions.
#3 QB
Graham Mertz: Starts preseason finale
Aug 23rd
Mertz completed 14 of 16 pass attempts for 145 yards and a touchdown in Saturday's 26-7 preseason win over Detroit.
#2 RB
Dameon Pierce: Early work in preseason finale
Aug 23rd
Pierce had seven carries for 17 yards in Saturday's 26-7 preseason win over the Lions.
#1 QB
C.J. Stroud: To be held out Saturday
Aug 23rd
Stroud and most other projected starters won't play in Saturday's preseason game against Detroit, Aaron Wilson of KPRC 2 Houston reports.
#1 LT
Cam Robinson: Returns to practice
Aug 19th
Robinson (leg) returned from a lower-leg injury to practice Monday, Aaron Wilson of KPRC 2 Houston reports.
#2 RT
Blake Fisher: DNP due to sprained ankle
Aug 18th
Fisher didn't practice Monday because of an ankle sprain, Aaron Wilson of KPRC 2 Houstonreports.