Playing in his third NBA season, Isaac appeared in 34 (32 starts) games for the Magic during 2019-20. He looked the part of a budding star while on the court, setting a host of new career highs: 11.9 points per game, a 47.0 field-goal percentage, 6.8 rebounds, 2.3 blocks and 1.6 steals across 28.8 minutes per contest. On Nov. 23, the 6-foot-11 forward supplied a career-high 25 points along with nine rebounds, four steals, four three-pointers and two blocks against the Pacers. On Dec. 15, Isaac generated 21 points, 11 rebounds, three assists and two steals during a win at New Orleans. Isaac notched multiple blocks in 23 of his 34 appearances, headlined by a career-high six rejections in a Nov. 6 game against the Mavericks. Against Toronto on Nov. 20, Isaac posted 16 points, 13 rebounds, three assists, and three blocks en route to one of his five double-doubles on the season. He went on to pick up a career-high seven steals against Milwaukee on Dec. 28, adding 19 points, nine rebounds, two assists and a block. On Jan. 1, Isaac suffered a knee injury that kept him out until the NBA restart. Isaac returned for a Jul. 31 matchup against the Nets, playing 16 minutes and finishing with 16 points and six rebounds. On Aug. 2, his second game back, Isaac sustained another knee injury, ending his season.2018
In his second NBA season, Isaac appeared in 75 games for the Magic, making 64 starts. The No. 6 overall pick in the 2017 NBA Draft, Isaac averaged 9.6 points and 5.4 rebounds per game, hitting 42.9 percent of his field goals, 32.3 percent of his three-pointers, and 81.5 percent of his free throws. He scored in double-digits 37 times and reached 15 points on 14 occasions. Isaac scored a career-high 20 points in a win over the Pelicans on Feb. 12. He recorded three double-doubles, including a career-best 13 boards against Indiana on Jan. 31. Isaac also blocked 1.3 shots per game, good for 19th in the league. He finished with 98 total blocks (20th in the NBA) and posted a block percentage of 4.1 percent (17th in the NBA). Isaac blocked five shots in a game on two separate occasions. In the Magic's first-round playoff series against the Raptors, Isaac started all five contests and posted two double-digit scoring efforts. He had 11 points, eight rebounds and three blocks in Orlando's Game 1 victory. In Game 3, Isaac posted a playoff-career-high 14 points to go with seven rebounds, two steals and two blocks in 29 minutes.2017
Isaac was drafted by the Orlando Magic with the sixth overall pick in the 2017 NBA Draft. The Florida State project battled hip soreness in Summer League play, but made his debut on time for the start of the regular season, recording four points, two blocks and eight rebounds in the Oct. 18 opener against Miami. He started the next two games in place of Aaron Gordon, who was sidelined with an ankle injury. In Isaac's first career start, he recorded nine points (4-5 FG, 1-1 3Pt), three rebounds and two steals in a loss to the Nets. Once Gordon was back, however, Isaac was back to a reserve role for the next 10 games, missing one contest in that stretch due to illness. Isaac's rookie season hit a snag Nov. 13, however, as he suffered an ankle injury that resulted in 17 games on the sidelines. He played in three of the next five games after his Dec. 17 return, but still battled ankle trouble along the way. Isaac was later shut down indefinitely to aid his recovery, and he even played two G-League games before returning to the Magic on March 2. He ended up playing 12 more games (eight starts) to finish the season, averaging 5.5 points, 3.6 rebounds and 1.9 steals. His career high of 15 points came in his last game of the regular season -- an April 1 loss to the Hawks. Isaac's rookie campaign was cut a bit short by injury, however, as he missed nine of the last 11 games with a foot strain and additional ankle trouble. There was not an opportunity to return in the postseason, as Isaac's Magic missed the playoffs with a record of 25-57.