Houston Texans vs San Francisco 49ers Odds, Week 8, 2025

#2 LT

Spencer Burford: Designated to return off IR

Oct 22nd

The 49ers designated Burford (knee) to return to practice on Wednesday.

#1 LCB

Renardo Green: Starts week with limited practice

Oct 22nd

Green (toe) was a limited participant at practice Wednesday, Vic Tafur of The Athletic reports.

#1 SCB

Upton Stout: Still nursing ankle issue

Oct 22nd

Stout (ankle) was a limited participant at practice Wednesday, Vic Tafur of The Athletic reports.

#1 RCB

Deommodore Lenoir: Tending to quad injury

Oct 22nd

Lenoir (quadricep) did not participate at practice Wednesday, Vic Tafur of The Athletic reports.

#2 WR

Ricky Pearsall: Another missed practice

Oct 22nd

Pearsall (knee) will not participate in Wednesday's practice, David Lombardi of SFStandard.com reports.

#1 QB

Brock Purdy: Remains limited in practice

Oct 22nd

Coach Kyle Shanahan said Purdy (toe) will be limited in practice Wednesday, Vic Tafur of The Athletic reports.

#1 WLB

Dee Winters: Notches three stops in Week 7

Oct 21st

Winters totaled three tackles (all solo) in Sunday's 20-10 win against Atlanta.

#1 FS

Malik Mustapha: Bumps up workload in Week 7

Oct 21st

Mustapha tallied six tackles (three solo) Sunday in a 20-10 win over the Falcons.

#2 FS

Marques Sigle: Sees playing time drop in Week 7

Oct 21st

Sigle recorded two tackles (one solo) while playing just 31 percent of San Francisco's defensive snaps in Sunday's 20-10 win over Atlanta.

#1 MLB

Tatum Bethune: Another big performance

Oct 20th

Bethune recorded 10 tackles (four solo), including one tackle for loss, in Sunday's 20-10 win over the Falcons.

#1 C

Jake Brendel: Expected to miss time with injury

Oct 20th

Head coach Kyle Shanahan said Monday that Brendel is expected to be sidelined for a couple of weeks due to a hamstring injury, Matt Maiocco of NBC Sports Bay Area reports.

#1 LDE

Bryce Huff: Set to miss time with hamstring strain

Oct 20th

San Francisco head coach Kyle Shanahan said Monday that Huff is expected to miss a couple weeks due to a hamstring strain, Matt Maiocco of NBC Sports Bay Area reports.

#3 TE

Jake Tonges: Reverts to reserve role

Oct 20th

Tonges logged eight snaps on offense (12 percent) and was not targeted in Sunday's 20-10 win over the Falcons.

#2 RB

Brian Robinson: Season-high 36 yards Sunday

Oct 20th

Robinson carried the ball nine times for 36 yards and was not targeted as a receiver in Sunday's 20-10 win over Atlanta.

#4 WR

Demarcus Robinson: Blanked as No. 3 WR Sunday

Oct 20th

Robinson failed to catch his only target in Sunday's 20-10 win over the Falcons.

#3 WR

Kendrick Bourne: Production peters out Sunday

Oct 19th

Bourne pulled in both of his targets for 14 yards in Sunday's 20-10 win over the Falcons.

#1 WR

Jauan Jennings: Gains 31 yards Sunday

Oct 19th

Jennings (ankle/ribs/shoulder) had four receptions on seven targets for 31 yards in Sunday's 20-10 win over Atlanta.

#1 TE

George Kittle: No catches in return from injury

Oct 19th

Kittle (hamstring) failed to bring in either of his targets in Sunday's 20-10 win over the Falcons.

#2 QB

Mac Jones: Gritty performance in win

Oct 19th

Jones (knee/oblique) completed 17 of 26 pass attempts for 152 yards and an interception while recording five rush attempts for 11 yards in Sunday's 20-10 win over the Falcons.

#1 RB

Christian McCaffrey: First 100-yard rushing game of 2025

Oct 19th

McCaffrey rushed 24 times for 129 yards and two touchdowns while bringing in seven of eight targets for 72 yards in Sunday's 20-10 win over the Falcons.

#2 DT2

Kevin Givens: Good to go Sunday night

Oct 19th

Givens (pectoral) is active for Sunday night's game against the Falcons.

#4 RB

Jordan James: Not playing Sunday night

Oct 19th

James (coach's decision) is inactive for Sunday Night Football against the Falcons.

#6 WR

Jordan Watkins: Inactive Sunday night

Oct 19th

Watkins (coach's decision) is inactive for Sunday night's matchup with the Falcons.

#2 MLB

Fred Warner: Officially placed on IR

Oct 18th

The 49ers placed Warner (ankle) on injured reserve Saturday.

#5 WR

Skyy Moore: Ready for Week 7

Oct 17th

Moore does not have an injury designation ahead of Sunday's game against the Falcons, Briana Jeannael of the 49ers' official site reports.

#8 WR

Jacob Cowing: Progressing in recovery

Oct 17th

Head coach Kyle Shanahan said Friday that Cowing (hamstring) is "getting close" to returning from injured reserve, Nick Wagoner of ESPN.com reports.

#2 LDE

Yetur Gross-Matos: Won't play vs. Falcons

Oct 17th

Gross-Matos (knee/hamstring) is listed as out for Sunday's game versus Atlanta, Nick Wagoner of ESPN.com reports.

#2 SS

Jason Pinnock: Moves into reserve role

Oct 14th

Pinnock played two snaps on special teams and none on defense in Sunday's 30-19 loss to the Buccaneers.

#7 WR

Brandon Aiyuk: Still no timetable to practice

Oct 13th

Coach Kyle Shanahan said Monday that Aiyuk (knee) is getting "closer and closer" to being able to practice, but the 49ers don't have a specific timeline for the wide receiver to do so, Nick Wagoner of ESPN.com reports.

#1 K

Eddy Pineiro: Connects on all four field goals

Oct 12th

Pineiro made all four of his field-goal attempts and his lone extra-point try during the 49ers' 30-19 loss to the Buccaneers on Sunday.

#2 LDT

Alfred Collins: Set to play vs. Tampa Bay

Oct 12th

Collins (knee) will play in the 49ers' matchup versus the Buccaneers on Sunday, Briana Jeannel of the team's official site reports.

#1 LDT

Kalia Davis: Will play Sunday

Oct 12th

Davis (hand) is active for San Francisco's matchup versus Tampa Bay on Sunday, Briana Jeannel of the team's official site reports.

#3 LDE

Robert Beal: Good to go for Week 6

Oct 10th

Beal (groin) doesn't carry an injury designation into Sunday's game against Tampa Bay, Greg Auman of Fox Sports reports.