Texans vs 49ers Odds, Lines, Spreads & Totals 2025
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BetMGM 
BetRivers 
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ESPN Bet 
Hard Rock 
49ers
23.5 Pts
Texans
22.0 Pts
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Moneyline
DraftKings
PROBABILITY with vig removed
49ers Win (-120)
52.2%
Texans Win (+100)
47.8%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
Spread
DraftKings
PROBABILITY with vig removed
Win By 2+ Pts(-108)
49.6%
Win or Lose By < 2 Pts(-112)
50.4%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
No changes have been recorded yet.
Over Under
DraftKings Points
PROBABILITY with vig removed
Over 46 Total Points(-115)
51.1%
Under 46 Total Points(-105)
48.9%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
No changes have been recorded yet.
Player Props
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49ers Injury Report
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Texans Injury Report
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49ers Lineup
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QB
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RB
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WR
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WR
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WR
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TE
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K
Inactives
None reported yet.
Texans Lineup
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QB
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RB
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WR
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WR
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WR
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TE
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K
Inactives
None reported yet.
49ers News
#2 K
Greg Joseph: Headed to 49ers
May 16th
The 49ers are slated to sign Joseph, Matt Barrows of The Athletic reports.
#1 QB
Brock Purdy: Gets massive five-year extension
May 16th
Purdy and the 49ers agreed to terms Friday on a five-year, $265 million contract extension, Tom Pelissero of NFL Network reports.
#5 LCB
Tre Tomlinson: Reverts to IR
May 13th
Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log.
#2 LT
Andre Dillard: Links up with 49ers
May 9th
The 49ers signed Dillard (concussion) on Friday, Jennifer Lee Chan of NBC Sports Bay Area reports.
#3 QB
Kurtis Rourke: Won't play in rookie camp
May 9th
Rourke (knee) won't participate in the 49ers' rookie camp, Matt Maiocco of NBC Sports Bay Area reports.
Texans News
#1 K
Ka'imi Fairbairn: Clears up cap space
May 12th
Fairbairn agreed to terms Monday on a contract restructure with the Texans for the purpose of freeing up salary cap space, Aaron Wilson of KPRC 2 Houston reports.
#1 DT2
Folorunso Fatukasi: Returning to Houston
May 7th
The Texans re-signed Fatukasi on Wednesday, DJ Bien-Aime of ESPN reports.
#2 FS
Jimmie Ward: Rehab progressing, already running
May 5th
Texans head coach DeMeco Ryans said Monday that Ward is "doing fine" in his recovery from foot surgery and "is starting to get back to running a little bit," Aaron Wilson of KPRC 2 Houston reports.
#3 WR
Tank Dell: Progressing, but return timeline TBD
May 5th
Texans coach DeMeco Ryans reiterated Monday that Dell (knee) remains without a timetable for return, Aaron Wilson of KPRC 2 Houston reports.