Injury news in soccer is notoriously sketchy, so while the below information should be used as a guide, always check the confirmed lineups before every match.
Note: this column is updated throughout the week as injury news is released.
v. 
BMO Field
Wednesday, Aug. 5 at 8:00 p.m. EDT
Toronto FC
Suspended:Jozy Altidore
Out:Mark Bloom (quad)
Doubtful:Josh Williams (coach's decision), Luke Moore (ankle)
Questionable:Michael Bradley (calf), Nick Hagglund (appendectomy)
Probable:Ashtone Morgan (groin), Clement Simonin (knee)
Orlando City SC
Out:Kaka (undisclosed), Harrison Heath (kneecap), Kevin Molino (knee), Brek Shea (groin)
Doubtful:Tony Cascio (back)
Questionable:Rafael Ramos (thigh)
v. 
Stade Saputo
Wednesday, Aug. 5 at 8:00 p.m. EDT
Montreal Impact
Suspended:Marco Donadel
Out:Kenny Cooper (knee), Cameron Porter (knee)
Doubtful:Hassoun Camara (knee), Adrian Lopez (knee), Justin Mapp (elbow)
Questionable:Didier Drogba (match fitness)
New York Red Bulls
Suspended:Damien Perrinelle
Out:Chris Duvall (leg)
Questionable:Ronald Zubar (groin)
Probable:Kemar Lawrence (international duty)
