New Orleans Saints vs San Francisco 49ers Odds, Week 2, 2025

#1 WR

Jauan Jennings: Optimism for Sunday

Sep 13th

Jennings, who is questionable to play Sunday against New Orleans due to a shoulder injury, is considered a game-time decision, though there is "optimism he goes," Ian Rapoport of NFL Network reports.

#3 TE

Brayden Willis: Back with active roster

Sep 13th

Willis was elevated from the 49ers' practice squad to the active roster Saturday.

#3 QB

Adrian Martinez: Elevated Saturday

Sep 13th

Martinez was elevated from the 49ers' practice squad to the active roster Saturday.

#4 RB

Jordan James: Good to go for Week 2

Sep 12th

James (finger) doesn't have an injury designation heading into Sunday's Week 2 contest against the Saints, Noah Furtado of the San Francisco Chronicle reports.

#1 LT

Trent Williams: Uncertain for Week 2

Sep 12th

Williams (knee) is questionable for Sunday's Week 2 game against New Orleans, Matt Maiocco of NBC Sports Bay Area reports.

#2 QB

Mac Jones: Getting first start under Shanahan

Sep 12th

Jones will start Sunday's game at New Orleans in place of Brock Purdy (toe), Adam Schefter of ESPN reports.

#5 WR

Jordan Watkins: Clear for potential pro debut

Sep 12th

Watkins (ankle) doesn't have a designation for Sunday's game in New Orleans, Noah Furtado of the San Francisco Chronicle reports.

#1 QB

Brock Purdy: Officially ruled out

Sep 12th

Purdy (toe) has been ruled out for Sunday's game at New Orleans, Matt Maiocco of NBC Sports Bay Area reports.

#2 LDE

Yetur Gross-Matos: Returns to practice Thursday

Sep 11th

Gross-Matos (knee) was a limited participant in Thursday's practice, Vic Tafur of The Athletic reports.

#1 TE

Luke Farrell: Increased reps on tap

Sep 10th

Farrell and Jake Tonges are in line for increased snaps, beginning Sunday versus the Saints, with starting tight end George Kittle (hamstring) having been placed on IR and out a minimum of four games, Dianna Russini, Vic Tafur and Matt Barrows of The Athletic report.

#2 TE

Jake Tonges: Opportunity knocks

Sep 10th

Tonges and Luke Farrell are in line for more snaps at tight end, beginning Sunday versus the Saints, with George Kittle (hamstring) on IR and set to miss at least four games, Dianna Russini, Vic Tafur and Matt Barrows of The Athletic report.

#1 K

Eddy Pineiro: Replacing Moody in San Francisco

Sep 9th

Pineiro agreed to a one-year contract with the 49ers on Tuesday, Adam Schefter of ESPN reports.

#4 TE

George Kittle: Move to IR official

Sep 9th

The 49ers placed Kittle (hamstring) on injured reserve Tuesday.

#1 RDE

Nick Bosa: Strip sack in win

Sep 8th

Bosa recorded six solo tackles, including 1.0 sacks, while also adding a forced fumble and a fumble recovery in Sunday's 17-13 win over the Seahawks.

#1 FB

Kyle Juszczyk: Gains 32 yards Sunday

Sep 8th

Juszczyk recorded two receptions for 32 yards on two targets in Sunday's 17-13 win over Seattle.

#4 WR

Marquez Valdes-Scantling: Plays role of decoy Sunday

Sep 8th

Valdes-Scantling logged 27 snaps on offense and did not receive a target in Sunday's 17-13 win over the Seahawks.

#6 WR

Skyy Moore: Handles return duties for SF

Sep 8th

Moore did not receive a target and returned five combined kicks for 63 yards in Sunday's 17-13 win over Seattle.

#3 RB

Isaac Guerendo: Limited to special teams

Sep 8th

Guerendo played 15 snaps on special teams and did not receive a carry in Sunday's 17-13 win over the Seahawks.

#2 RB

Brian Robinson: Gets 10 touches in SF debut

Sep 8th

Robinson rushed nine times for 33 yards and had one reception for four yards on two targets in Sunday's 17-13 win over Seattle.

#3 WR

Kendrick Bourne: Reuniting with Niners

Sep 8th

Bourne has agreed to terms Monday on a one-year contract worth up to $5 million with San Francisco, Adam Schefter of ESPN reports.

#1 MLB

Fred Warner: Plays well in Week 1

Sep 8th

Warner tallied eight total tackles (four solo), including one tackle for loss, in Sunday's 17-13 win over the Seahawks.

#1 RT

Colton McKivitz: Inks extension with San Francisco

Sep 8th

McKivitz signed a three-year, $45 million extension with the 49ers on Monday, Adam Schefter of ESPN reports.

#2 WR

Ricky Pearsall: Leads team with 108 receiving yards

Sep 7th

Pearsall brought in four of seven targets for 108 yards in Sunday's 17-13 win over Seattle.

#1 RB

Christian McCaffrey: Racks up 142 yards from scrimmage

Sep 7th

McCaffrey (calf) handled 22 carries for 69 yards and nine receptions for 73 yards on 10 targets in Sunday's 17-13 win over the Seahawks.

#1 FS

Marques Sigle: Gets starting nod Week 1

Sep 7th

Sigle will be the 49ers' starting safety against the Seahawks on Sunday, Matt Maiocco of NBC Sports Bay Area reports.

#1 RG

Dominick Puni: Ready to face Seahawks

Sep 5th

Puni (knee) does not have an injury designation ahead of Sunday's game against the Seahawks, Michael-Shawn Dugar of The Athletic reports.

#1 LG

Ben Bartch: Full practice Wednesday

Sep 3rd

Bartch (elbow) was a full participant at the 49ers' practice Wednesday, Cam Inman of The San Jose Mercury News reports.

#2 RDE

Sam Okuayinonu: Logs full practice Wednesday

Sep 3rd

Okuayinonu (shoulder) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#2 DT2

CJ West: Logs full practice Wednesday

Sep 3rd

West (knee) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#1 SCB

Upton Stout: Recovered from calf injury

Sep 3rd

Stout (calf) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#1 LDE

Mykel Williams: Full participant in practice

Sep 3rd

Williams (knee) practiced in full Wednesday, Cam Inman of The San Jose Mercury News reports.

#1 RCB

Deommodore Lenoir: Recovered from hip injury

Sep 3rd

Lenoir (hip) was not listed on the 49er's injury report Wednesday, Cam Inman of The San Jose Mercury News reports.