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McCaffrey rushed 22 times for 57 yards and brought in eight of nine targets for 82 yards and a touchdown in the 49ers' 26-23 overtime win over the Rams on Thursday night.
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Pineiro went 4-for-4 on field-goal tries and made both of his extra-point attempts in Thursday's 26-23 overtime win over the Rams.
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Winters is back in the game Thursday night after briefly leaving with a shoulder issue, Matt Maiocco of NBC Sports Bay Area reports.
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Gross-Matos has a hamstring injury and has been ruled out for the rest of Thursday's game against the Rams, Eric Branch of the San Francisco Chronicle reports.
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Davis (hand) has been ruled out for the rest of Thursday night's game against the Rams, Ian Rapoport of NFL Network reports.
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Davis (hand) is questionable to return to Thursday's game against the Rams, Eric Branch of the San Francisco Chronicle reports.
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Kittle has had no setbacks while on injured reserve due to a hamstring injury and has a chance to return Week 6 at Tampa Bay, Ian Rapoport of NFL Network reports.
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West (thumb) is active for Thursday's game against the Rams, Briana Jeannel of the 49ers' official site reports.
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James (coach's decision) is inactive for Thursday night's game against the Rams, Briana Jeannel of the 49ers' official site reports.
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The 49ers elevated Turner from the practice squad to the active roster ahead of Thursday night's game against the Rams.
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The 49ers signed Martinez from the practice squad to the active roster ahead of Thursday's game against the Rams.
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Beal (groin) has been ruled out for Thursday night's contest against the Rams, Matt Barrows of The Athletic reports.
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Green (neck) doesn't carry an injury designation into Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
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Winters (knee) doesn't carry an injury designation into Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
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Watkins (calf) has been ruled out for Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
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Jones (knee) will start Thursday at the Rams after Brock Purdy (toe) was ruled out for that contest, Matt Maiocco of NBC Sports Bay Area reports.
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Pearsall (knee) is ruled out for Thursday's game against the Rams, Matt Maiocco of NBC Sports Bay Area reports.
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Jennings (ankle, ribs) is ruled out for Thursday's matchup against the Rams, Matt Maiocco of NBC Sports Bay Area reports.
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Purdy (toe) has been ruled out for Thursday's game at the Rams, Matt Maiocco of NBC Sports Bay Area reports.
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Watkins (calf) was a non-participant in Tuesday's walk-through practice.
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Jones (knee) was listed as a full participant at the 49ers' walkthrough Tuesday, Vic Tafur of The Athletic reports.
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Sigle logged eight tackles (six solo) and one pass defense during the 49ers' 26-21 loss to the Jaguars on Sunday.
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Head coach Kyle Shanahan said that Jennings (ankle/ribs) won't participate in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
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Head coach Kyle Shanahan said that Pearsall (knee) won't participate in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
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Purdy (toe) will be a non-participant in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
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