Injury news in soccer is notoriously sketchy, so while the below information should be used as a guide, always check the confirmed lineups before every match.
Note: this column is updated as injury news is released.
v. 
Sporting Park
Friday, September 18 at 7:00 p.m. EDT
Sporting Kansas City
Out:Roger Espinoza (foot), Ike Opara (Achilles)
Questionable:Tim Melia (leg), Chance Myers (hamstring), Amobi Okugo (knee)
FC Dallas
Doubtful:Bakary Soumare (concussion)
Questionable:Mauro Diaz (quad), Dan Kennedy (knee), Victor Ulloa (knee)
v. 
BMO Field
Saturday, September 19 at 2:00 p.m. EDT
Toronto FC
Out:Mark Bloom (quad)
Questionable:Jackson (quad), Daniel Lovitz (foot)
Colorado Rapids
Doubtful:Luis Solignac (hamstring)
Questionable:Axel Sjoberg (knock)
v. 
BC Place Stadium
Saturday, September 19 at 7:00 p.m. EDT
Vancouver Whitecaps FC
Suspension:Matias Laba
Doubtful:Andre Lewis (knee), Ben McKendry (knee)
Seattle Sounders
Out:Roman Torres (knee)
Doubtful:Andres Correa (thigh)
Questionable:Chad Barrett (hamstring), Andy Craven (knee), Leonardo Gonzalez (hamstring), Damion Lowe (hip), Chad Marshall (knock), Nelson Valdez (undisclosed)
Probable:Brad Evans (concussion), Troy Perkins (personal)
v. 
Yankee Stadium
Saturday, September 19 at 7:00 p.m. EDT
New York City FC
Suspended:Sebastian Velasquez
Out:George John (knee), Tony Taylor (knee)
Doubtful:Connor Brandt (hernia), Javier Calle (hamstring)
Questionable:Iraola (calf), David Villa (hamstring)
San Jose Earthquakes
Out:Innocent (knee), Steven Lenhart (knee), Jordan Stewart (Achilles)
Doubtful:Jean-Baptiste Pierazzi (foot)
Questionable:Victor Bernardez (hamstring), Paulo Renato (quad), Khari Stephenson (calf)
v. 
RFK Memorial Stadium
Saturday, September 19 at 7:00 p.m. EDT
D.C. United
Out:Chris Korb (knee)
Questionable:Davy Arnaud (concussion)
Columbus Crew
Out:Sagi Lev-Ari (knee)
Doubtful:Gaston Sauro (head)
v. 
Stade Saputo
Saturday, September 19 at 8:00 p.m. EDT
Montreal Impact
SuspensionAmbroise Oyongo
Out:Cameron Porter (knee)
Doubtful:Kenny Cooper (knee), Adrian Lopez (knee)
Questionable:Patrice Bernier (foot), Justin Mapp (toe)
ProbableEvan Bush (rest), Marco Donadel (rest), Didier Drogba (toe), Ignacio Piatti (calf)
New England Revolution
Suspended:London Woodberry
Out:Darrius Barnes (knee)
v. 
Toyota Park
Saturday, September 19 at 8:30 p.m. EDT
Chicago Fire
Suspended:Matt Polster
Out:Adailton (abdomen)
QuestionableEric Gehrig (heel), Kennedy Igboananike (ankle), Gilberto (back/hamstring)
Orlando City SC
Out:Conor Donovan (knee), Harrison Heath (kneecap), Kevin Molino (knee)
Questionable:Darwin Ceren (knee), Kaka (leg)
Probable:Corey Ashe (undisclosed)
v. 
Rio Tinto Stadium
Saturday, September 19 at 9:30 p.m. EDT
Real Salt Lake
Out:Chris Schuler (foot)
QuestionableLuis Silva (calf)
Probable:Sebastian Jaime (personal)
Los Angeles Galaxy
Out:Brian Perk (ankle)
Doubtful:Todd Dunivant (calf)
Questionable:Raul Mendiola (concussion), Jose Villareal (knee)
v. 
Providence Park
Saturday, September 20 at 5:00 p.m. EDT
Portland Timbers
Out:Ben Zemanski (knee)
New York Red Bulls
Suspended:Connor Lade, Dax McCarty
Out:Chris Duvall (leg), Roy Miller (knee)
v. 
PPL Park
Saturday, September 20 at 7:00 p.m. EDT
Philadelphia Union
Doubtful:Maurice Edu (groin), Jimmy McLaughlin (concussion)
Questionable:Fred (quad), Andrew Wenger (knee)
Houston Dynamo
Suspension:Raul Rodriguez
Out:Jermaine Taylor (quad)
Doubtful:Rob Lovejoy (hamstring)
Questionable:DaMarcus Beasley (calf), Luis Garrido (hamstring), Alex (hamstring), Kofi Sarkodie (knee)
