CeeDee Lamb could have one of his biggest games playing against a Lions defense that's tougher against the run than the pass.
Ja'Marr Chase should keep rolling against a Colts secondary with poor boundary corner personnel.
The Indianapolis secondary is weakest on the boundary and downfield, where Mike Evans is at his best.
Playing at home and against the Bears, the Week 11 setup couldn't be much easier for Amon-Ra St. Brown.
Erik Siegrist previews the Monday night games as Nick Chubb and the Browns face the division-rival Steelers on the road in the nightcap.
The Colts' cornerback personnel is weak but their run defense is strong, setting up a feast for Calvin Ridley and the Jags passing game.
There's pressure on Keenan Allen to step up with Mike Williams out, and the Jaguars defense appears vulnerable in the slot.
Chris Olave could finish his remarkable rookie season in strong fashion against Carolina's backup corners.
Amon-Ra St. Brown is providing monstrous late-season production again and should continue against Minnesota.
A.J. Brown has both a good matchup and the Revenge Game narrative in Week 13.
It's been an encouraging breakout season for Christian Kirk, but he draws a buzzsaw assignment against Marlon Humphrey.
Erik Siegrist previews the Monday night matchup as Jonathan Taylor and the Colts take on the visiting Steelers.
Xavien Howard is more of a ballhawk than a shutdown corner, so Amari Cooper should do well in the warm weather Sunday.
With better coverage in the seam than the perimeter, expect Mike Evans to hit the ground running against the Chiefs.
Mario Puig analyzes the wide receiver-cornerback matchups for Week 3. Allen Robinson is poised to finally break out after a slow two-week start to his Rams career.