Tanner Roark, WAS vs. TEX ($41): Roark is in a groove of late, having won three straight contests, lasting seven innings in each while allowing five runs and striking out 18 in 21.2 frames. He'll face a Rangers lineup that strikes out 23.3 percent of the time against right handers and has just a .293 wOBA and .173 ISO on the road.
Brad Peacock, HOU vs. LAA ($32): Longevity isn't Peacock's forte, as he's made it out of the fifth inning in just one of his three starts since moving into the rotation, so he'll need to be a bit more economical if he's to notch a victory. But he owns a massive 42.4 percent strikeout rate in those three starts, making up for the lack of innings pitched. Facing an Angels offense that ranks last in the league with a .131 ISO away from home, third to last in wOBA at .283 and numbers that are just marginally better against right handers (.146/.298) shouldn't instill much worry.
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Mike Zunino, SEA vs. TOR ($10): Zunino looks to have figured things out at the plate a bit since his recall on May 23, having slashed .326/.360/.624. He's hit four home runs in 13 games, giving him as much upside as any at this price and position, and he's done most of his damage against right handers, owning a 1.106 OPS. Jays' starter Joe Biagini has a 6.04 ERA on the road compared to 1.01 at home, allowing 1.46 homers per nine to righties.
Lucas Duda, NYM at ATL ($18): Braves' starter Julio Teheran continues to give up runs at will at home, owning an 8.40 ERA compared to 2.95 on the road. He's allowing lefties to post a 1.194 OPS and .488 wOBA at SunTrust Park, having allowed a whopping seven long balls to 77 batters faced. Duda likely comes as the less obvious choice to exploit that over outfielder Michael Conforto, and boasts a .397 wOBA, .957 OPS and 151 wRC+ against righties.
Chris Taylor, LAD vs. CIN ($16): Stacking the Dodgers against Reds' starter Amir Garrett is certainly on the table, as Garrett has been shelled over his last three starts for 21 runs over 11.2 frames. He's allowing right handers a .374 wOBA and 11 of his 15 home runs allowed have come to that handedness, while Taylor sports a .391 wOBA and 148 wRC+ against lefties, second on the team behind the injured Justin Turner.
Jose Ramirez, CLE vs. CWS ($15): Ramirez is a much better hitter from the left side, slashing .310/.375/.535 against right handers against .256/.306/.397 against southpaws. White Sox starter Miguel Gonzalez comes in with a 5.74 ERA and minimal 11.1 percent strikeout rate on the road, while allowing a .377 wOBA to left handers.
Jordy Mercer, PIT vs. MIA ($15): Mercer is among the hottest players at his position, batting .367 (11-of-30) with four extra base hits since May 31. He's been solid against right handed arms all season, owning a .349 wOBA and 118 wRC+ entering a matchup with Vance Worley, who carries a 6.75 ERA on the road.
Marcell Ozuna, MIA at PIT ($19): Using either Ozuna or Giancarlo Stanton against struggling Pirates starter Tyler Glasnow seems prudent. Glasnow owns a 6.98 ERA and is allowing righties to post a .371 wOBA and .876 OPS against him. Ozuna owns a .398 wOBA, 149 wRC+ and .277 ISO against righties, all numbers that are higher than Stanton's, and come with a $3 savings.
Ender Inciarte, ATL vs. NYM ($17): Inciarte has hit safely in 21 of his last 24 outings and entered Wednesday having gone 10-for-16 over his last four games while adding four walks. His .409 wOBA and 155 wRC+ at home against righties should play well against Mets' starter Matt Harvey, who is allowing a .398 wOBA to lefties on the road.
Andrew Benintendi, BOS vs. DET ($13): Benintendi is showing signs of breaking out of a funk that plagued him through the latter part of May, having gone 6-of-13 over his last four games entering Wednesday, with three homers to boot. He brings a modest .330 wOBA against righties into the game but has shown much better power against them, with all eight of his homers and all but one of his extra base hits coming against that handedness. Tigers' starter Jordan Zimmerman has a 7.07 ERA on the road, and has been particularly vulnerable to left-handed bats, allowing a .490 wOBA and 1.186 OPS to them.