Menu
Fantasy Home
NFL Betting

Patriots vs Steelers Odds, Lines, Spreads & Totals 2025

Steelers
22.5 Pts
Patriots
21.0 Pts
Sunday September 21, 2025 at 1:00 PM ET
Loading Possible Bets...
Player Props
Loading Advanced NFL Stats...
PIT
Steelers Injury Report
Loading Steelers Injuries...
NE
Patriots Injury Report
Loading Patriots Injuries
PIT
Steelers Lineup
Inactives
    None reported yet.
NE
Patriots Lineup
Inactives
    None reported yet.
PIT
Steelers News
#1 RDE
Derrick Harmon: Not playing Week 2 vs. Seattle
Sep 9th
Head coach Mike Tomlin announced Tuesday that Harmon (knee) has been ruled out for the Steelers' Week 2 contest against the Seahawks on Sunday, Alan Saunders of SteelersNow.com reports.
#1 SS
DeShon Elliott: Won't play Week 2
Sep 9th
Head coach Mike Tomlin said Tuesday that Elliott (knee) will not play in the Steelers' Week 2 contest against the Seahawks on Sunday, NFL reporter Jordan Schultz reports.
#2 SS
Jabrill Peppers: Strikes deal with Pittsburgh
Sep 9th
Peppers and the Steelers agreed to a contract Tuesday, Ian Rapoport and Mike Garafolo of NFL Network report.
#1 ROLB
Alex Highsmith: Leading tackler in win
Sep 8th
Highsmith recorded eight tackles (five solo), with 1.0 sacks, during the Steelers' win versus the Jets on Sunday.
#1 LOLB
T.J. Watt: Tallies five tackles
Sep 8th
Watt logged five tackles (three solo) and a pass deflection during Pittsburgh's win over the Jets on Sunday.
#4 WR
Ben Skowronek: Scores touchdown in Week 1 victory
Sep 8th
Skowronek secured his lone target for a 22-yard touchdown in Sunday's 34-32 win over the Jets.
#3 WR
Roman Wilson: Not targeted in season opener
Sep 8th
Wilson wasn't targeted during the Steelers' 34-32 win over the Jets on Sunday.
#1 TE
Jonnu Smith: Finds end zone in team debut
Sep 8th
Smith secured five of six targets for 15 yards and a touchdown during Sunday's 34-32 win over the Jets.
#2 TE
Pat Freiermuth: Tallies three receptions in victory
Sep 8th
Freiermuth secured all three of his targets for 28 yards during Sunday's 34-32 win over the Jets.
#2 RB
Kenneth Gainwell: Limited production in Week 1
Sep 8th
Gainwell rushed seven times for 19 yards while securing three of four targets for four yards during Sunday's 34-32 win over the Jets.
#3 RB
Kaleb Johnson: Minimal involvement in debut
Sep 7th
Johnson rushed the ball once for minus-2 yards in Sunday's 34-32 win over the Jets. He also returned five kickoffs for 132 yards.
#1 RB
Jaylen Warren: Makes impact as receiver
Sep 7th
Warren rushed the ball 11 times for 37 yards in Sunday's 34-32 win over the Jets. He added two receptions on two targets for 22 yards and a touchdown.
#1 K
Chris Boswell: Connects on game-winning FG
Sep 7th
Boswell went 2-for-2 on field-goal attempts while making all four of his extra-point tries in Sunday's 34-32 win over the Jets.
#1 WR
DK Metcalf: Racks up 83 yards in Steelers debut
Sep 7th
Metcalf recorded four receptions on seven targets for 83 yards in Sunday's 34-32 win over the Jets.
#1 QB
Aaron Rodgers: Four touchdowns in revenge game
Sep 7th
Rodgers completed 22 of 30 passes for 244 yards, four touchdowns and no interceptions in Sunday's 34-32 win over the Jets.
#1 RCB
Joey Porter: Dealing with hamstring issue
Sep 7th
Porter is dealing with hamstring tightness after Sunday's 34-32 win over the Jets.
#2 LILB
Malik Harrison: Suffers knee injury, won't return
Sep 7th
Harrison has been ruled out for the rest of Sunday's game against the Jets due to a knee injury, Ray Fittipaldo of the Pittsburgh Post-Gazette reports.
#3 QB
Skylar Thompson: Inactive, serving as emergency QB
Sep 7th
Thompson (hamstring) is inactive for Sunday's Week 1 clash against the Seahawks but is listed as Pittsburgh's emergency third quarterback, Teresa Varley of the Steelers' official site reports.
#2 ROLB
Nick Herbig: Not suiting up Week 1
Sep 7th
Herbig (hamstring) is inactive for Sunday's matchup against Seattle, Teresa Varley of the Steelers' official site reports.
#1 LDE
Cameron Heyward: Gets revised deal, will play Week 1
Sep 6th
Heyward and the Steelers agreed to a revised contract Saturday that adds more than $3 million in new-money incentives, Mike DeFabo of The Athletic reports.
#2 LT
Calvin Anderson: Not listed on injury report
Sep 3rd
Anderson (undisclosed) wasn't listed on Pittsburgh's injury report Wednesday, Teresa Varley of the team's official site reports.
#1 LS
Christian Kuntz: Not on injury report
Sep 3rd
Kuntz (chest) wasn't listed on Pittsburgh's injury report Wednesday, Teresa Varley of the team's official site reports.
#1 NT
Keeanu Benton: Back to full health
Sep 3rd
Benton (upper body) wasn't listed on Wednesday's injury report.
#2 WR
Calvin Austin: Ducks injury report
Sep 3rd
Austin (abdomen) isn't listed on the injury report for Sunday's game against the Jets.
#2 SCB
Donte Kent: Lands on IR
Aug 28th
The Steelers placed Kent on injured reserve Thursday due to a foot injury, Teresa Varley of the team's official site reports.
#4 QB
Will Howard: Sent to IR
Aug 28th
The Steelers placed Howard (hand) on injured reserve Thursday, Teresa Varley of the team's official site reports.
#4 NT
Domenique Davis: Reverts to IR
Aug 27th
Davis (undisclosed) reverted to injured reserve with the Steelers on Wednesday, Alan Saunders of SteelersNow.com reports.
#2 LCB
Cory Trice: Sidelined to begin 2025
Aug 27th
Trice (hamstring) was placed on injured reserve Tuesday, Teresa Varley of Steelers.com reports.
NE
Patriots News
#1 LOLB
Harold Landry: Impressive outing in Patriots debut
Sep 8th
Landry recorded five total tackles (four solo), including 2.5 sacks, in Sunday's 20-13 loss to the Patriots.
#1 SS
Jaylinn Hawkins: Impresses in Week 1
Sep 8th
Hawkins recorded five total tackles (all solo), including 1.0 sacks, and one interception in Sunday's 20-13 loss to the Raiders.
#1 LILB
Robert Spillane: Just three tackles vs. Las Vegas
Sep 8th
Spillane recorded three total tackles (all solo) in Sunday's 20-13 loss to the Raiders.
#5 WR
Kyle Williams: One catch in regular-season debut
Sep 8th
Williams was on the field for seven of a possible 71 snaps on offense in Sunday's 20-13 loss to the Raiders, Mike Reiss of ESPN.com reports.
#4 WR
Mack Hollins: One catch in opener
Sep 8th
Hollins, who was on the field for 40 of a possible 71 snaps on offense in Sunday's 20-13 loss to the Raiders, per Mike Reiss of ESPN.com, caught one of his two targets in the contest for three yards.
#1 TE
Hunter Henry: Four catches Sunday
Sep 8th
Henry caught four of his eight targets for 66 yards in the Patriots' 20-13 loss to the Raiders on Sunday.
#2 TE
Austin Hooper: One catch in Week 1
Sep 8th
Hooper logged 23 of a possible 71 snaps on offense in Sunday's 20-13 loss to the Raiders, Mike Reiss of ESPN.com reports.
#3 RB
Antonio Gibson: Minor role in opener
Sep 8th
Gibson was on the field for five of a possible 71 snaps on offense in Sunday's 20-13 loss to the Raiders, Mike Reiss of ESPN.com reports.
#1 K
Andres Borregales: Misses one FG in loss
Sep 7th
Borregales went 2-for-3 on field-goal attempts and made his lone extra-point try in the Patriots' 20-13 loss to the Raiders on Sunday.
#2 WR
Kayshon Boutte: Breaks out for 100-yard effort
Sep 7th
Boutte brought in six of eight targets for 103 yards in the Patriots' 20-13 loss to the Raiders on Sunday.
#3 WR
DeMario Douglas: Minimal production in Week 1 loss
Sep 7th
Douglas secured two of seven targets for minus-2 yards and a touchdown while rushing once for four yards in the Patriots' 20-13 loss to the Raiders on Sunday.
#1 RB
Rhamondre Stevenson: Limited to nine touches in loss
Sep 7th
Stevenson rushed seven times for 15 yards and brought in two of three targets for 12 yards in the Patriots' 20-13 loss to the Raiders on Sunday.
#1 QB
Drake Maye: High-volume passing day in loss
Sep 7th
Maye completed 30 of 46 passes for 287 yards with a touchdown and an interception and added four rushes for 11 yards in the Patriots' 20-13 loss to the Raiders on Sunday. He also committed a fumble recovered by New England.
#1 WR
Stefon Diggs: Remains involved in Week 1 loss
Sep 7th
Diggs secured six of seven targets for 57 yards in the Patriots' 20-13 loss to the Raiders on Sunday.
#2 RB
TreVeyon Henderson: Clears 50 total yards in debut
Sep 7th
Henderson rushed five times for 27 yards and brought in all six targets for 24 yards in the Patriots' 20-13 loss to the Raiders on Sunday. He also returned two kickoffs for 43 yards.
#1 LT
Will Campbell: Cleared to make NFL debut
Sep 7th
Campbell (ankle) is active for Sunday's game against the Raiders, Evan Lazar of the Patriots' official site reports.
#3 QB
Tommy DeVito: QB3 for Week 1
Sep 7th
DeVito (coach's decision) is inactive but will serve as the Patriots' emergency third-string quarterback against the Raiders on Sunday.
#6 WR
Efton Chism: Inactive for opener
Sep 7th
Chism is inactive for Sunday's season opener against the Raiders.
#2 RCB
Charles Woods: Ruled out Sunday
Sep 6th
Woods (groin) has been ruled out for Sunday's game against the Raiders.
#1 RCB
Christian Gonzalez: Out for Week 1
Sep 5th
The Patriots ruled out Gonzalez (hamstring) for Sunday's game against the Raiders, Evan Lazar of the Patriots' official site reports.
#1 FB
Jack Westover: Shifts to FB
Sep 2nd
Westover is now listed as a fullback on the Patriots' official depth chart, Evan Lazar of the Patriots' official site reports.
#3 LG
Layden Robinson: Heading to IR
Aug 27th
Robinson (undisclosed) was reverted to IR by the Patriots on Wednesday, per the NFL's official transaction log.
#3 RILB
Jahlani Tavai: Ends up on IR
Aug 27th
Tavai (undisclosed) was placed on injured reserve Tuesday.